The Effect of Cardiometabolic Control and Malnutrition on the Prevalence and Prognosis of Diabetic Retinopathy in Type 2 Diabetes

Melek Özdemi̇r, Yaşar Dağ, Mehmet Uzunlulu, A. Oguz, Aylin Ardagi̇l, Ömer Acar, Bensu Selbest
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Abstract

Purpose:It is estimated that type 2 diabetes mellitus affects 530 million people worldwide and 10.5 per cent of these patients have diabetic retinopathy. This study aims to investigate the predictive value of cardiometabolic control, GGT and malnutrition-related inflammation markers for predicting Diabetic retinopathy prevalence and prognosis. Materials and Methods:Type 2 Diabetes Mellitus patients who were consecutively admitted to Internal and Ophthalmology outpatient clinics were included in this study. Clinical, haematological and biochemical data were recorded. Cut-off values of GGT, PNI, NRI and HALP scores were determined by receiver operator characteristic curve analysis. Univariate and multivariate analyses were performed to determine the association of all variables with Diabetic retinopathy. As a result, we evaluated which of these tests were predictive and prognostic for the development of diabetic retinopathy. Results:This study included 166 patients. Fasting blood glucose(p
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心血管代谢控制和营养不良对 2 型糖尿病视网膜病变患病率和预后的影响
目的:据估计,全球有 5.3 亿人患有 2 型糖尿病,其中 10.5% 的患者患有糖尿病视网膜病变。本研究旨在探讨心脏代谢控制、谷丙转氨酶和营养不良相关炎症指标对糖尿病视网膜病变患病率和预后的预测价值。材料与方法:本研究纳入了连续在内科和眼科门诊就诊的 2 型糖尿病患者。记录了临床、血液学和生化数据。通过受体运算特征曲线分析确定了 GGT、PNI、NRI 和 HALP 评分的临界值。我们进行了单变量和多变量分析,以确定所有变量与糖尿病视网膜病变的关系。因此,我们评估了这些测试中哪些对糖尿病视网膜病变的发生具有预测性和预后性。结果:本研究包括 166 名患者。空腹血糖(p
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