COMPARISON OF ROPIVACAINE ALONE VS ROPIVACAINE WITH METHYLPREDNISOLONE INJECTION AS A TREATMENT OF TRIGGER POINTS FOR MYOFASCIAL PAIN: A SUPERIORITY RANDOMIZED CLINICAL TRIAL

S. Mushtaq, KM Bhatti, Q. Nawaz, K. Bashir, Aur Ghafoor
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Abstract

Soft tissue rheumatism, known as myofascial pain syndrome (MPS), is typified by taut bands, transferred pain that is distinct, sensory alterations that occur, and a local twitch response. It is also connected with trigger points in one or more muscles. The purpose of the research is to evaluate the effects of injections of Ropivacaine alone vs. Ropivacaine with methylprednisolone in decreasing pain in people in our community who have myofascial pain caused by trigger points. The design of this study was a randomized controlled trial. This study was carried out from July 2022 to August 2023. The research comprised 50 individuals (27 females and 23 males) diagnosed with MPS who came to our clinic. Using online randomization software, the patients were randomly divided into two groups. Group B got a mixture of 0.25% Ropivacaine & 10mg methylprednisolone in 3ml normal saline at each trigger point, whereas Group A received 3ml of 0.25% Ropivacaine. Dry needling of trigger sites was done in both groups. Patients were assessed at two, four, and eight weeks of intervention. The patients' pre-treatment assessment measures showed no statistically significant differences. After 4 and 8 weeks of assessment, Group B NRS pain and BDI scores showed statistically significant improvements compared to pre-treatment results (p<0.05). NRS and BDI scores were reduced in group A compared to their pretreatment values, but that was not clinically significant. Results of our study showed that there was a statistically significant difference between both groups in terms of pain, stress, and anxiety after the intervention. Ropivacaine with methylprednisolone gave better results than Ropivacaine alone in reducing pain and anxiety among the study population.
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罗哌卡因单独注射与罗哌卡因联合甲基强的松龙注射治疗肌筋膜痛触发点的比较:优越性随机临床试验
软组织风湿病被称为肌筋膜疼痛综合征(MPS),其典型特征是绷带、明显的转移性疼痛、感觉改变和局部抽搐反应。它还与一块或多块肌肉的触发点有关。这项研究的目的是评估单独注射罗哌卡因与罗哌卡因联合甲基强的松龙对减轻社区中由触发点引起的肌筋膜疼痛患者的疼痛的效果。本研究设计了一项随机对照试验。研究时间为 2022 年 7 月至 2023 年 8 月。研究对象包括 50 名前来本诊所就诊的肌筋膜疼痛患者(27 名女性和 23 名男性)。通过在线随机化软件,患者被随机分为两组。B 组在每个触发点注射 0.25% 罗哌卡因和 10 毫克甲基强的松龙混合物,再加入 3 毫升生理盐水;而 A 组则注射 3 毫升 0.25% 罗哌卡因。两组均对触发点进行干针治疗。患者在干预后的两周、四周和八周接受评估。患者治疗前的评估结果显示,两组患者在统计学上没有显著差异。经过 4 周和 8 周的评估,B 组患者的 NRS 疼痛评分和 BDI 评分与治疗前相比有明显改善(P<0.05)。与治疗前相比,A 组的 NRS 和 BDI 评分有所下降,但没有临床意义。我们的研究结果表明,干预后两组患者在疼痛、压力和焦虑方面的差异具有统计学意义。在减轻研究对象的疼痛和焦虑方面,罗哌卡因联合甲基强的松龙比单独使用罗哌卡因效果更好。
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