Pap smear in Early Detection of Cervical Precancerous Lesions in Erbil

Avin Wlya Muhammad
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Abstract

Background and objectives: Cervical cancer remains common. This may be because Iraq has no cervical cancer screening or human papilloma virus vaccination program. The goal of the study is to figure out how well the Pap smear works as a way to find cervical precancerous lesions also identify the prevalence of cervical cancer among women and to identify the potential risk factors for cervical cancer. Methods: A prospective cross-sectional study conducted using closed end questionnaire tool for the purpose of data collection which started from 1st of October 2021 until 1st of September 2022. Convenient type of sampling was used in collecting data which include 470 women attending to cervical screening unit in Maternity Teaching Hospital, Erbil, Kurdistan Region /Iraq. The questionnaire composed of two main parts including the socio-demographic data of the patients such as age, gender, occupation, education level, religion, income status, age at the marriage, duration of marriage…etc. The result of pap smear and cone biopsy performed during colposcopy procedure to match the accuracy of pap smear. Results: The findings revealed that 36% of the women aged between 40-49 years, the majority (80%) of them were married at the age of 15-24 years, 30% of their marriage lasted from 4-14 years, and most (72.6%) of them were housewives. The result of sensitivity, accuracy, positive and negative predicted value was equal to 45.6%, 97.7%, 80%, 89.9% respectively. The kappa test was 0.52 which indicate agreement between screening and gold standard test is a diagnosis of cervical cancer is still colposcopy-guided biopsy, which is then staged on the basis of the clinical examination and the outcome of imaging procedures, most obtained results were statistically significant. Conclusion: Pap smear had a lower sensitivity, but a higher specificity in the current study. The most common complaint of the women was post-coital bleeding. Severe acute cervicitis was the most common finding for the Pap smear.
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巴氏涂片在埃尔比勒宫颈癌前病变早期检测中的应用
背景和目的:宫颈癌仍然很常见。这可能是因为伊拉克没有开展宫颈癌筛查或人类乳头瘤病毒疫苗接种计划。本研究的目的是了解巴氏涂片作为一种发现宫颈癌前病变的方法的效果如何,同时确定宫颈癌在妇女中的发病率,并确定宫颈癌的潜在风险因素。研究方法从 2021 年 10 月 1 日到 2022 年 9 月 1 日,使用封闭式问卷工具收集数据,进行前瞻性横断面研究。在收集数据时采用了方便抽样法,其中包括在伊拉克库尔德斯坦地区埃尔比勒市妇产教学医院宫颈筛查科就诊的 470 名妇女。问卷由两大部分组成,包括患者的社会人口学数据,如年龄、性别、职业、教育程度、宗教信仰、收入状况、结婚年龄、婚姻持续时间......等。阴道镜检查过程中进行的子宫颈抹片检查和锥形活检的结果,以与子宫颈抹片检查的准确性相匹配。结果:调查结果显示,36% 的妇女年龄在 40-49 岁之间,其中大多数(80%)的结婚年龄为 15-24 岁,30% 的婚姻持续时间为 4-14 年,大多数(72.6%)的妇女是家庭主妇。灵敏度、准确度、正预测值和负预测值的结果分别为 45.6%、97.7%、80% 和 89.9%。卡帕检验的结果为 0.52,表明筛查与金标准检验之间的一致性,即宫颈癌的诊断仍然是阴道镜引导下的活检,然后根据临床检查和影像学检查的结果进行分期,所获得的结果大多具有统计学意义。结论在本次研究中,子宫颈抹片检查的敏感性较低,但特异性较高。妇女最常见的主诉是性交后出血。严重的急性宫颈炎是子宫颈抹片检查最常见的结果。
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