Two years recurrence rate of ovarian and endometrial malignancies following Surgical versus clinical staging

Abstract

Background and objectives: Gynecological cancers represent a big burden on national health institutes. Recurrences of these cancers are documented frequently that needed more efforts to prevent or reduce them. The aim of the study was to know the difference between Standard Surgical Staging and Non-Standard Surgical Staging in gynecological cancers in terms of recurrence rate. Methods: This study was a retrospective cross-sectional study conducted at the Maternity Teaching Hospital and Hiwa Hospital in Sulaymaniyah city-Kurdistan region/Iraq over two years from June 2020 to June 2022, on sample of 86 women with gynecological cancer divided into two study groups (42 women underwent standard surgical staging and 44 women underwent non-standard surgical staging). Standard surgical staging for endometrial and ovarian cancers included midline laparotomy, peritoneal washout, samples from the right and left sub-diaphragmatic surfaces, infracoloic Omentectomy, total abdominal hysterectomy & bilateral salpingo-oophorectomy, any peritoneal deposits and pelvic and para-aortic Lymphadenectomy in maternity hospital Results: The recurrence rate in women with non-standard surgical staging were 25% (p=0.009), while in women with standard surgical staging were 4.8%. 11 women with non-standard surgical staging had advanced cancer stages at recurrence compared to 2 cases with standard surgical staging. Although no significant difference in death outcome between both study groups (p=0.09), no woman who underwent standard surgical staging with recurrence died, while the death rate of women underwent non-standard surgical staging with recurrence was (63.6%) Conclusions: The standard surgical staging in women with gynecological cancer is important in the recurrence rate of these cancers.