STUDY OF THE HISTOLOGICAL AND BIOCHEMICAL EFFECT OF INSTANT NOODLES ON THE KIDNEY AND LIVER ON RATS MODEL

Mohammed Ibrahim, Rilwan Isah Tsamiya, Promise Oladipo, Bala Gaius
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Abstract

Instant noodle is produced from flour, and sold in dried form in packets. The noodles are easy and quick in preparation to eat, it can also eat as snacks or as main food. The aim of this research is to investigate the effects of noodle with and without seasoning on the histology as well as biochemical parameters of liver and kidney on rats’ model. Three groups of 5 Wistar rats were used, they were fed with noodle with and without seasoning for the period of 28 days. After 28 days the blood of rats was collected for biochemical analysis, the rats were also sacrificed, liver and kidney were removed for histological analysis. Histological results show only a little change in the architecture of the liver and kidney, but only small amount of fat droplet in liver section. The Liver and Kidney tests didn’t show any changes in their parameters, only little increase in urea level of the kidney. Conclusively from this research, it was revealed no much effect of consuming instant noodle in rat model.
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方便面对大鼠肝肾组织学和生化影响的研究
方便面由面粉制成,以干面条的形式包装出售。这种面条食用方便快捷,既可作为零食,也可作为主食。本研究的目的是调查方便面加调味料和不加调味料对大鼠肝脏和肾脏组织学和生化指标的影响。研究人员使用了三组 5 只 Wistar 大鼠,分别用加调味料和不加调味料的面条喂养它们 28 天。28 天后,收集大鼠血液进行生化分析,并将大鼠处死,取出肝脏和肾脏进行组织学分析。组织学结果显示,肝脏和肾脏的结构仅有轻微变化,但肝脏切片中仅有少量脂肪滴。肝脏和肾脏的检测指标没有发生任何变化,只是肾脏的尿素水平略有上升。这项研究最终表明,食用方便面对大鼠模型没有太大影响。
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