Pengaruh Positifitas Leukosit Esterase dan Nitrit Urine Terhadap Nilai Neutrophil Lymphocyte Ratio (NLR) pada Pasien Infeksi Saluran Kemih

Jurnal Kesehatan Andalas Pub Date : 2024-03-03 DOI:10.25077/jka.v12i3.2240

Citra Dian Kholisha, Siti Zaetun, Y. Jiwantoro, Ersandhi Resnhaleksmana

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Abstract

Urinary tract infection (UTI) characterized by positivity of leukocyte esterase and nitrite can affect the Neutrophil Lymphocyte Ratio (NLR) value as a reflection of the degree of infection and inflammation by pathogenic microorganisms. Objective: To analyzed the effect of positivity leukocyte esterase and nitrite urine on NLR values in UTI patients. Methods: This study used an observational analytic method with a cross-sectional approach. UTI patients will be subjected to urinalysis and complete blood cell examination. The data obtained will be subjected to the Pearson correlation and linear regression tests. Results: This study used 36 samples of UTI patients with an abnormal number of positive leukocyte esterase samples in 36 samples (100%), positive urine nitrite in 20 samples (55,6%), and abnormal NLR values >3,5 are 27 samples (75%) with a mean of 10,21. Conclusion: There is a significant influence and relationship between the positivity of leukocyte esterase and urine nitrite on NLR value in UTI patients with a simultaneous value of 45,1% and p 0,000.Keywords: UTI, leukocyte esterase, urine nitric, NLR

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白细胞酯酶阳性和尿亚硝酸盐对尿路感染患者中性粒细胞淋巴细胞比值（NLR）的影响

以白细胞酯酶和亚硝酸盐阳性为特征的尿路感染（UTI）会影响中性粒细胞淋巴细胞比率（NLR）值，从而反映病原微生物感染和炎症的程度。研究目的分析尿液中白细胞酯酶和亚硝酸盐阳性对尿毒症患者 NLR 值的影响。方法本研究采用横断面观察分析方法。尿毒症患者将接受尿液分析和全血细胞检查。获得的数据将进行皮尔逊相关和线性回归测试。结果：本研究使用了 36 份尿毒症患者样本，其中 36 份样本（100%）出现白细胞酯酶阳性异常，20 份样本（55.6%）出现尿亚硝酸盐阳性，27 份样本（75%）出现 NLR 值大于 3.5 的异常，平均值为 10.21。结论是白细胞酯酶阳性和尿亚硝酸盐对UTI患者的NLR值有明显的影响和关系，两者的同时值为45.1%，P为0.000： UTI、白细胞酯酶、尿亚硝酸盐、NLR

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Jurnal Kesehatan Andalas

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24 weeks