Wendy L.A. Nichols, Emily S. Coffey, Claire A. Knapp
{"title":"Drugs affecting the heart: anti-hypertensives","authors":"Wendy L.A. Nichols, Emily S. Coffey, Claire A. Knapp","doi":"10.1016/j.mpaic.2024.01.008","DOIUrl":null,"url":null,"abstract":"<div><p>Many patients presenting for surgery are established on anti-hypertensive medication or may require additional manipulation of blood pressure perioperatively. This article aims to explore the pharmacology of antihypertensives in relation to cardiovascular physiology, focusing on the effects on the renin–angiotensin system and the autonomic nervous system. The most recent guidance for the stepwise treatment for hypertension is reviewed, aiming to provide anaesthetists with the relevant knowledge to manage hypertensive patients perioperatively.</p></div>","PeriodicalId":45856,"journal":{"name":"Anaesthesia and Intensive Care Medicine","volume":"25 4","pages":"Pages 273-280"},"PeriodicalIF":0.2000,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anaesthesia and Intensive Care Medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1472029924000080","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Many patients presenting for surgery are established on anti-hypertensive medication or may require additional manipulation of blood pressure perioperatively. This article aims to explore the pharmacology of antihypertensives in relation to cardiovascular physiology, focusing on the effects on the renin–angiotensin system and the autonomic nervous system. The most recent guidance for the stepwise treatment for hypertension is reviewed, aiming to provide anaesthetists with the relevant knowledge to manage hypertensive patients perioperatively.
期刊介绍：
Anaesthesia and Intensive Care Medicine, an invaluable source of up-to-date information, with the curriculum of both the Primary and Final FRCA examinations covered over a three-year cycle. Published monthly this ever-updating text book will be an invaluable source for both trainee and experienced anaesthetists. The enthusiastic editorial board, under the guidance of two eminent and experienced series editors, ensures Anaesthesia and Intensive Care Medicine covers all the key topics in a comprehensive and authoritative manner. Articles now include learning objectives and eash issue features MCQs, facilitating self-directed learning and enabling readers at all levels to test their knowledge. Each issue is divided between basic scientific and clinical sections. The basic science articles include anatomy, physiology, pharmacology, physics and clinical measurement, while the clinical sections cover anaesthetic agents and techniques, assessment and perioperative management. Further sections cover audit, trials, statistics, ethical and legal medicine, and the management of acute and chronic pain.
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