Massive pseudotumor of unknown etiology in a cemented metal-on-polyethylene total hip arthroplasty: a case report.

IF 0.5 4区 医学 Q4 ORTHOPEDICS Annals of Joint Pub Date : 2022-10-15 eCollection Date: 2022-01-01 DOI:10.21037/aoj-22-3
Aaron Gazendam, Karim Masrouha, Snezana Popovic, Michelle Ghert, David Wilson
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Abstract

Background: The formation of destructive pseudotumors is a well-documented, albeit rare, complication of total hip arthroplasties. They tend to be progressive and, if left untreated, can result in extensive periprosthetic bony destruction. The current case presents a large benign mass consistent with a pseudotumor on both imaging and intraoperative findings but histologic findings demonstrating chronic hematoma.

Case description: An 86-year-old female with a metal-on-polyethylene total hip presented with a massive pseudotumor accompanied by extensive bony lysis. Due to pain and chronic anemia, a palliative debulking procedure was undertaken as a palliative measure. At one year follow-up, the patient reported significant pain relief and was able to ambulate safely with gait aids. Her hemoglobin stabilized post-operatively and ongoing transfusions were not required. Final pathology was not supportive of particle disease despite this being the leading diagnosis. Microscopic sections showed tissue mostly composed of fibrin and blood with multiple foci of calcification and reactive papillary endothelial hyperplasia which can be seen in chronic hematomas.

Conclusions: This case presents the diagnostic dilemma of a large benign mass consistent with a pseudotumor on both imaging and intraoperative findings but histologic findings consistent with a chronic hematoma. It highlights the importance of close follow-up and early intervention when periprosthetic osteolysis is detected.

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病因不明的骨水泥聚乙烯金属全髋关节置换术大面积假瘤:病例报告。
背景:破坏性假瘤的形成是全髋关节置换术的一种并发症,尽管罕见,但已得到充分证实。假瘤往往呈进行性发展,如果不及时治疗,可导致假体周围大面积骨质破坏。本病例中的大块良性肿块在影像学和术中发现均与假瘤一致,但组织学结果显示为慢性血肿:一位86岁的女性患者,其髋关节为金属聚乙烯全髋关节,并伴有巨大的假瘤和广泛的骨质溶解。由于疼痛和慢性贫血,患者接受了姑息性剥脱手术。在一年的随访中,患者表示疼痛明显缓解,并能在步态辅助工具的帮助下安全行走。术后她的血红蛋白趋于稳定,无需继续输血。最终病理结果不支持颗粒疾病,尽管这是主要诊断。显微镜切片显示组织主要由纤维蛋白和血液组成,并伴有多个钙化灶和反应性乳头状内皮增生,这在慢性血肿中很常见:本病例的影像学和术中检查结果均符合假瘤,但组织学检查结果却与慢性血肿一致,这是一个巨大良性肿块的诊断难题。它强调了在发现假体周围溶骨时密切随访和早期干预的重要性。
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来源期刊
Annals of Joint
Annals of Joint ORTHOPEDICS-
CiteScore
1.10
自引率
-25.00%
发文量
17
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