Synergism Between Hypothalamic Astrocytes and Neurons in Metabolic Control.

IF 5.3 2区 医学 Q1 PHYSIOLOGY Physiology Pub Date : 2024-07-01 Epub Date: 2024-03-26 DOI:10.1152/physiol.00009.2024
Laura M Frago, Alfonso Gómez-Romero, Roberto Collado-Pérez, Jesús Argente, Julie A Chowen
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Abstract

Astrocytes are no longer considered as passive support cells. In the hypothalamus, these glial cells actively participate in the control of appetite, energy expenditure, and the processes leading to obesity and its secondary complications. Here we briefly review studies supporting this conclusion and the advances made in understanding the underlying mechanisms.

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下丘脑星形胶质细胞和神经元在新陈代谢控制中的协同作用
星形胶质细胞不再被视为被动的支持细胞。在下丘脑中,这些胶质细胞积极参与控制食欲、能量消耗和导致肥胖及其继发性并发症的过程。在此,我们简要回顾了支持这一结论的研究以及在了解其潜在机制方面取得的进展。
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来源期刊
Physiology
Physiology 医学-生理学
CiteScore
14.50
自引率
0.00%
发文量
37
期刊介绍: Physiology journal features meticulously crafted review articles penned by esteemed leaders in their respective fields. These articles undergo rigorous peer review and showcase the forefront of cutting-edge advances across various domains of physiology. Our Editorial Board, comprised of distinguished leaders in the broad spectrum of physiology, convenes annually to deliberate and recommend pioneering topics for review articles, as well as select the most suitable scientists to author these articles. Join us in exploring the forefront of physiological research and innovation.
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