Clinical Characteristics and Severity of Respiratory Syncytial Virus Infection in Korean Children during the Post-COVID-19 Pandemic Period.

IF 2.8 Q2 INFECTIOUS DISEASES Infection and Chemotherapy Pub Date : 2024-03-01 Epub Date: 2024-03-13 DOI:10.3947/ic.2023.0076
Ye Eun Kim, Dayun Kang, Ji Soo Park, Eun Hwa Choi, Ki Wook Yun
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Abstract

We aimed to evaluate the clinical features of respiratory syncytial virus (RSV) infection and risk factors for severe RSV disease among Korean children in 2022/2023. A total of 235 children were identified, and 84.3% were hospitalized. Patients under 3 months and 2 years of age accounted for 20.9% and 54.5%, respectively. Pneumonia was diagnosed in 40.9% of children and bronchiolitis in 23.8%. Respiratory support and intensive care were required in 43.4% and 7.7% of patients, respectively. Haemophilus influenzae nasopharyngeal colonization and the presence of underlying disease showed a significant correlation with severity indicators. The clinical impact of RSV infection was high on infants and toddlers, even those having no underlying disease or not being indicated for palivizumab.

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后 COVID-19 大流行时期韩国儿童呼吸道合胞病毒感染的临床特征和严重程度。
我们的目的是评估 2022/2023 年韩国儿童呼吸道合胞病毒(RSV)感染的临床特征和严重 RSV 疾病的风险因素。共发现 235 名儿童,其中 84.3% 住院治疗。3个月以下和2岁以下的患者分别占20.9%和54.5%。40.9%的儿童被诊断为肺炎,23.8%的儿童被诊断为支气管炎。分别有 43.4% 和 7.7% 的患者需要呼吸支持和重症监护。鼻咽部流感嗜血杆菌定植和基础疾病的存在与严重程度指标有显著相关性。RSV感染对婴幼儿的临床影响很大,即使是那些没有基础疾病或没有帕利珠单抗适应症的婴幼儿也不例外。
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来源期刊
Infection and Chemotherapy
Infection and Chemotherapy INFECTIOUS DISEASES-
CiteScore
6.60
自引率
11.90%
发文量
71
审稿时长
22 weeks
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