Antimicrobial effects of cannabidiol on select agriculturally important Clostridia

IF 2.5 3区 生物学 Q3 MICROBIOLOGY Anaerobe Pub Date : 2024-03-25 DOI:10.1016/j.anaerobe.2024.102843
Jourdan E. Lakes , Jessica L. Ferrell , Mark A. Berhow , Michael D. Flythe
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Abstract

Amino acid-fermenting Clostridia have undesirable effects in agricultural systems, which can be mitigated by antibiotics, but resistance necessitates alternatives. Here, we demonstrate the efficacy of cannabidiol on growth and ammonia inhibition of five agriculturally relevant Clostridia: Clostridium sporogenes, Peptostreptococcus spp., Clostridioides difficile, Acetoanaerobium sticklandii, and Clostridium aminophilum.

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大麻二酚对某些重要农业梭菌的抗菌作用。
氨基酸发酵梭状芽孢杆菌在农业系统中具有不良影响,抗生素可以减轻这些影响,但抗药性需要替代品。在这里,我们展示了大麻二酚对五种与农业相关的梭状芽孢杆菌(Clostridium sporogenes)、Peptostreptococcusspp.、难辨梭状芽孢杆菌(Clostridioides difficile)、Acetoanaerobium sticklandii 和嗜氨基梭状芽孢杆菌(Clostridium aminophilum)的生长和氨抑制作用。
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来源期刊
Anaerobe
Anaerobe 生物-微生物学
CiteScore
5.20
自引率
8.70%
发文量
137
审稿时长
76 days
期刊介绍: Anaerobe is essential reading for those who wish to remain at the forefront of discoveries relating to life processes of strictly anaerobes. The journal is multi-disciplinary, and provides a unique forum for those investigating anaerobic organisms that cause infections in humans and animals, as well as anaerobes that play roles in microbiomes or environmental processes. Anaerobe publishes reviews, mini reviews, original research articles, notes and case reports. Relevant topics fall into the broad categories of anaerobes in human and animal diseases, anaerobes in the microbiome, anaerobes in the environment, diagnosis of anaerobes in clinical microbiology laboratories, molecular biology, genetics, pathogenesis, toxins and antibiotic susceptibility of anaerobic bacteria.
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