Stability distillation hypothesis for the origin of life

Cheng Bi
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Abstract

The essence of life is a frequency distribution conversion process of molecules accompanied by changes in information. In wet-dry cycling hot springs, RNA of different sequences continuously undergoes polymerization and decomposition reactions, products with stable configurations will accumulate their frequency among all RNA molecules and finally become an important source of DNA coding and non-coding regions in primitive cells. This periodic extreme environmental change narrows the frequency distribution of macromolecules through the distillation process and new potential catalysts are searched. When enough macromolecules are accumulated and reliable reaction pathways are built, phospholipids randomly wrap the macromolecules in the hot springs which I would call it the pioneer pools, and these protocells become parallel calculators of molecule frequency distribution. Through the selective permeability of the cell membrane to different molecular weights and properties, cells with appropriate distribution have more opportunities to absorb small molecule substances and increase its intracellular frequencies of molecules. This will strongly induce the occurrence of macromolecules that can widely catalyze the synthesis of other macromolecules or themselves, such as ribosomes, etc. Rupture and fusion during cell division make all protocells share the same frequency distribution of molecules during the origin of life, thus ensuring that all present cells have very similar genetic materials and protein translation systems. This also suggests that viruses may have originated and evolved together with cells.
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生命起源的稳定蒸馏假说
生命的本质是伴随着信息变化的分子频率分布转换过程。在干湿循环的温泉中,不同序列的RNA不断发生聚合和分解反应,构型稳定的产物在所有RNA分子中的频率不断累积,最终成为原始细胞中DNA编码区和非编码区的重要来源。这种周期性的极端环境变化会通过蒸馏过程缩小大分子的频率分布,并寻找新的潜在催化剂。当积累了足够多的大分子并建立了可靠的反应途径后,磷脂就会随机地将大分子包裹在温泉中,我称之为先驱池,这些原细胞就成了分子频率分布的平行计算器。通过细胞膜对不同分子量和性质的选择性渗透,具有适当分布的细胞有更多机会吸收小分子物质,并增加其细胞内的分子频率。这将强烈诱导能广泛催化其他大分子或自身合成的大分子的出现,如核糖体等。细胞分裂过程中的破裂和融合使得所有原细胞在生命起源过程中分子的频率分布相同,从而保证了现在的所有细胞都具有非常相似的遗传物质和蛋白质翻译系统。这也表明病毒可能与细胞一起起源和进化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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