Management of Otitis externa with Ayurvedic formulation Gandhak Rasayana- A case report

IF 1.7 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Journal of Ayurveda and Integrative Medicine Pub Date : 2024-03-01 DOI:10.1016/j.jaim.2024.100893
Sandip Patil, Pravin Bhat
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Abstract

Otitis externa is an inflammatory and infectious disease that affects the external auditory canal. The term otorrhea refers to the outflow of discharge from the ear which is one of the main symptoms of otitis externa along with inflammation. External ear canal pathology or middle ear illness with tympanic membrane perforation is the etiological factor of otorrhea. Otorrhea is an indication of infection. Antimicrobial agents are the conventional treatment of various bacterial and fungal infections, but they have impediments such as resistance development, side effects, patient affordability, etc. The Gandhak Rasayana formulation mentioned in the Ayurvedic text can be a good option for the treatment of various infectious diseases. Karnasrava is a type of ear disease referred to as Vata predominant Tridoshaja disease and it is curable. The term Karnasrava signifies discharge from ear and is self-explanatory. Karnasrava consists of a wide spectrum of diseases and can have a near correlation with otitis externa as per signs and symptoms. Gandhak Rasayana exhibited significant antibacterial, antifungal and anti-inflammatory activity in otitis externa. Evaluating its antibacterial and antifungal activity can provide scientific evidence for the study through the present case report.

A 31-year-old male patient registered in OPD at Sane Guruji Hospital, Hadapsar, Pune was clinically diagnosed as Karnasrava (Otitis externa) and pus culture positive for Klebsiella species.

We started the treatment with Gandhak Rasayana-an Ayurvedic formulation of 250mg two tablets in the morning and evening with lukewarm water for 21 days. The outcome of the treatment was observed as a reduction in Karnashula (otalgia), Karnasrava (ear discharge), Karnakandu (itching), ear blockage and inflammatory changes. Post-treatment culture was negative for the organism. The improvement was noted in Brighton grading scale from grade III to grade I.

Gandhak Rasayana showed significant antibacterial activity in the present case. Evaluating its antibacterial, antifungal and anti-inflammatory activity can provide scientific evidence for the study.

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用阿育吠陀配方 Gandhak Rasayana 治疗外耳道炎--病例报告
外耳道炎是一种影响外耳道的炎症性和传染性疾病。耳溢是指耳内有分泌物流出,是外耳道炎的主要症状之一。外耳道病变或鼓膜穿孔的中耳疾病是导致耳溢的病因。耳鸣是感染的征兆。抗菌剂是治疗各种细菌和真菌感染的传统方法,但存在抗药性产生、副作用、患者负担不起等问题。阿育吠陀经文中提到的 Gandhak Rasayana 配方可以很好地治疗各种感染性疾病。Karnasrava 是一种耳部疾病,被称为 Vata predominant Tridoshaja 疾病,是可以治愈的。Karnasrava 一词表示耳部分泌物,其含义不言自明。Karnasrava 包含多种疾病,根据症状和体征,它与外耳道炎几乎是相关的。Gandhak Rasayana 对外耳道炎具有显著的抗菌、抗真菌和消炎活性。一名 31 岁的男性患者在普纳 Hadapsar 的 Sane Guruji 医院手术室登记,临床诊断为卡纳斯拉瓦耳炎(外耳道炎),脓培养克雷伯氏菌阳性。治疗结果显示,Karnashula(耳痛)、Karnasrava(耳流脓)、Karnakandu(瘙痒)、耳堵塞和炎症变化均有所减轻。治疗后的细菌培养呈阴性。Gandhak Rasayana 在本病例中显示出显著的抗菌活性。对其抗菌、抗真菌和抗炎活性进行评估可为研究提供科学依据。
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来源期刊
Journal of Ayurveda and Integrative Medicine
Journal of Ayurveda and Integrative Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
4.70
自引率
12.50%
发文量
136
审稿时长
30 weeks
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