Chemical Strategies of Tailoring PEDOT:PSS for Bioelectronic Applications: Synthesis, Processing and Device Fabrication

IF 9.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY CCS Chemistry Pub Date : 2024-04-02 DOI:10.31635/ccschem.024.202403858

Yewei Huang, Lingfeng Tang, Yuanwen Jiang

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Abstract

Poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) has been the most prominent conducting polymer due to its outstanding electrical properties, chemical stability, biocompatibility, and commercial availability. In this mini review, we aim to comprehensively outline the chemical approaches employed in tailoring PEDOT:PSS for bioelectronic applications. We open our discussion by showcasing various synthetic techniques and commercially accessible forms of PEDOT:PSS, providing practical advice and approaches to greatly enhance its electrical properties, and presenting diverse chemical designs and processing methods that are essential for converting PEDOT:PSS into different form factors, such as fibers, gels, and films, for integration a range of device structures. Additionally, we explore several burgeoning applications of PEDOT:PSS in bioelectronics, ranging from wearable health monitoring to implantable neural interfaces, underscoring its essential impact on improving device efficiency and biological compatibility, as it opens avenues for innovative diagnostic and therapeutic techniques in the realm of precision medicine. Concluding with an outlook, the review presents insights into the ongoing challenges and future research paths for PEDOT:PSS in the ever-evolving landscape of bioelectronics. We emphasize the need for continued innovation in materials science and engineering to further harness the full potential of this dynamic domain.

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为生物电子应用定制 PEDOT:PSS 的化学策略：合成、加工和器件制造

聚(3,4-亚乙二氧基噻吩):聚苯乙烯磺酸盐（PEDOT:PSS）因其出色的电性能、化学稳定性、生物相容性和商业可用性，一直是最突出的导电聚合物。在这篇小型综述中，我们旨在全面概述为生物电子应用定制 PEDOT:PSS 所采用的化学方法。我们通过展示 PEDOT:PSS 的各种合成技术和商业化形式展开讨论，提供实用的建议和方法以大大提高其电气性能，并介绍各种化学设计和加工方法，这些方法对于将 PEDOT:PSS 转变为不同的形式因素（如纤维、凝胶和薄膜）以集成各种设备结构至关重要。此外，我们还探讨了 PEDOT:PSS 在生物电子学中的几种新兴应用，从可穿戴健康监测到植入式神经接口，强调了它对提高设备效率和生物兼容性的重要影响，因为它为精准医疗领域的创新诊断和治疗技术开辟了道路。综述以展望结束，深入分析了 PEDOT:PSS 在不断发展的生物电子学领域中面临的挑战和未来的研究方向。我们强调需要在材料科学和工程学领域不断创新，以进一步发挥这一动态领域的全部潜力。下载图表下载 PowerPoint

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来源期刊

CCS Chemistry Chemistry-General Chemistry

CiteScore

13.60

自引率

13.40%

发文量

475

审稿时长

10 weeks

期刊介绍： CCS Chemistry, the flagship publication of the Chinese Chemical Society, stands as a leading international chemistry journal based in China. With a commitment to global outreach in both contributions and readership, the journal operates on a fully Open Access model, eliminating subscription fees for contributing authors. Issued monthly, all articles are published online promptly upon reaching final publishable form. Additionally, authors have the option to expedite the posting process through Immediate Online Accepted Article posting, making a PDF of their accepted article available online upon journal acceptance.