Tamizaje de cáncer colorrectal: pruebas emergentes no invasivas

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Revista Medica Clinica Las Condes Pub Date : 2024-03-01 DOI:10.1016/j.rmclc.2024.03.006
Alessandra Cassana , Mario Abedrapo , Mauricio Diaz , Diego Zamorano , Alejandro Zárate
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Abstract

Colorectal cancer (CRC) is the second cause of cancer in Chile and represents a public health problem due to its high morbidity and mortality. In the last 20 years, a progressive increase in its incidence has been described in patients under 50 years old. Early screening in general population is indicated in asymptomatic patients over 45 years old and has been shown to have an impact on mortality. The genetic and pathophysiological features of CRC make it susceptible to be screened using many strategies. The objective of this work is to review the latest emerging non-invasive screening methodologies currently being studied and developed using fecal, blood and urine samples, which may improve patient adherence to colorectal cancer screening programs.

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结直肠癌筛查:新出现的无创检测方法
结肠直肠癌(CRC)是智利第二大癌症病因,因其发病率和死亡率高而成为公共卫生问题。在过去 20 年中,50 岁以下患者的发病率逐渐上升。早期筛查适用于 45 岁以上的无症状患者,并已证明对死亡率有影响。由于 CRC 的遗传和病理生理特点,可采用多种策略对其进行筛查。这项工作的目的是回顾目前正在研究和开发的使用粪便、血液和尿液样本的最新无创筛查方法,这些方法可提高患者对结直肠癌筛查计划的依从性。
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来源期刊
Revista Medica Clinica Las Condes
Revista Medica Clinica Las Condes MEDICINE, GENERAL & INTERNAL-
CiteScore
0.80
自引率
0.00%
发文量
65
审稿时长
81 days
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