Tailor-made glycans

IF 38.1 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Nature reviews. Chemistry Pub Date : 2024-04-04 DOI:10.1038/s41570-024-00598-y
Sugyeom Kim, George A. O’Doherty
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Abstract

A highly chemoselective method for the insertion of carbohydrates into existing oligosaccharides has been developed. The reaction sequence involves a selective Lewis-acid catalysed cleavage of one glycosidic bond followed by sequential construction of two new glycosidic bonds.

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我们开发了一种高化学选择性方法,用于将碳水化合物插入现有的寡糖中。反应顺序包括选择性路易斯酸催化裂解一个糖苷键,然后依次构建两个新的糖苷键。
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来源期刊
Nature reviews. Chemistry
Nature reviews. Chemistry Chemical Engineering-General Chemical Engineering
CiteScore
52.80
自引率
0.80%
发文量
88
期刊介绍: Nature Reviews Chemistry is an online-only journal that publishes Reviews, Perspectives, and Comments on various disciplines within chemistry. The Reviews aim to offer balanced and objective analyses of selected topics, providing clear descriptions of relevant scientific literature. The content is designed to be accessible to recent graduates in any chemistry-related discipline while also offering insights for principal investigators and industry-based research scientists. Additionally, Reviews should provide the authors' perspectives on future directions and opinions regarding the major challenges faced by researchers in the field.
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