The Potential Ameliorative Effect of Empagliflozin on Myocardium in Cardiorenal Syndrome 3 via Targeting Mitophagy and Mitochondrial Biogenesis in Adult Male Albino Rat Model: Biochemical, Histological and Immunohistochemical Study

Marwa Yousry, Sarah Alghandour
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Abstract

. Results: AKI induced a significant rise in serum urea, creatinine, cardiac TNF-α, H 2 O 2 levels, P 62 , cytochrome-C area percentage, besides a non-significant
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Empagliflozin 通过靶向白化成年雄性大鼠的线粒体吞噬和线粒体生物生成对心肾综合征 3 心肌的潜在改善作用:生化、组织学和免疫组化研究
.结果AKI 会导致血清尿素、肌酐、心脏 TNF-α、H 2 O 2 水平、P 62、细胞色素-C 面积百分比显著升高,而非显著降低。
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