A clinico-pathological study of minor salivary gland tumors: experience of our institute

Sourabh Sharma, Vikesh Kumar, Konark Thakkar, Yugam Prasad Shandilya
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Abstract

Background: Minor salivary glands are found throughout the entire upper aerodigestive tract. Minor salivary gland neoplasms represent less than 25% of intraoral salivary neoplasms. There are no uniform guidelines at present for treatment for minor salivary gland tumors as these are rare entities. The objective of the study was to evaluate the clinicopathological profile of minor salivary gland tumors and to evaluate follow up of patients after treatment. Methods: The present study was a prospective observational study conducted on 11 patients of the Pacific Medical College and Hospital, Udaipur from 1 December 2020 to 31 December 2023 with complaints of intra-oral swelling with biopsy proven MSGT were included. Results: Out of 11 patients, 7 were female and 4 were male. Highest incidence was found in patients in the 4th-5th decade of life. For most patients, painless swelling was the primary presentation. The most common site for minor salivary cancer was the hard palate 55%. The most common histological types were adenocystic carcinoma. In 10 cases complete surgical excision with clear margins was the preferred mode of treatment. In 1 palliative therapy was required. Among 11 patients, 2 required radiotherapy. Conclusions: MSGT are rare, early diagnosed and resection with wide margins/neck dissections + SOS adjuvant therapy is key to treatment.
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唾液腺小肿瘤的临床病理研究:我院的经验
背景:小唾液腺遍布整个上消化道。小唾液腺肿瘤占口内唾液腺肿瘤的比例不到 25%。由于小唾液腺肿瘤比较罕见,目前还没有统一的治疗指南。本研究的目的是评估唾液腺小肿瘤的临床病理学特征,并评估患者治疗后的随访情况:本研究是一项前瞻性观察研究,纳入了乌代布尔太平洋医学院和医院 2020 年 12 月 1 日至 2023 年 12 月 31 日期间主诉口腔内肿物并经活检证实为 MSGT 的 11 名患者:结果:11 名患者中有 7 名女性和 4 名男性。第 4-5 个十年期的患者发病率最高。大多数患者主要表现为无痛性肿胀。小涎腺癌最常见的发病部位是硬腭,占 55%。最常见的组织学类型是腺囊肿癌。10例患者首选的治疗方式是边缘清晰的完全手术切除。1例需要姑息治疗。11例患者中有2例需要接受放射治疗:结论:MSGT非常罕见,早期诊断和边缘清晰的切除术/颈部切除术+SOS辅助治疗是治疗的关键。
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