Comparative evaluation of the biological activity of quercetin-like compounds

Abstract

   Objective. To determine the degree of manifestation of antioxidant, oncoprotective, anti-inflammatory properties of quercetin-like compounds of a number of flavonoids based on a comparative analysis of the complexing activity of oxygen-containing functional groups.   Materials and methods. Analysis and systematization of literary data, a rationalistic method of modeling the properties of molecular systems.   Results. The expediency of determining the structural identity of separate sections of molecules of various flavonoids for the subsequent determination of the degree of correlation of their biological properties is shown.   Conclusion. Comparison of biological properties of substances of plant origin in combination with application of the latest extraction methods will help to accelerate drug development at the stage of obtaining a new active substance.