Indonesian Indonesian Medicine Plants for Mental Health Disorders: Anxiety and Depression

Vivi Septya Wati, Irmanida Batubara, Budi Arifin, S. Indariani, Anggia Murni, Wong Shi Xuan, Yutaka Kuroki
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Abstract

Mental health disorders are currently widely discussed, especially anxiety and depression. The number of people living with anxiety and depression disorders in 2020 increased significantly due to the COVID-19 pandemic. These mental health disorders are quite serious and need to be addressed. Indonesian people for generations have used medicinal plants in everyday life, one of which is to treat symptoms of mental health disorders such as increasing mood and motivation, calming, overcoming depression, stress, anxiety, and sleep disorders. However, there has been no comprehensive review on the ethnopharmacology of Indonesian medicinal plants that can treat mental health disorders such as depression and anxiety and there is also little scientific evidence to support the efficacy of these plants. This paper reviews Indonesian medicinal plants used to treat mental health disorders and reviews the scientific evidence for these plants. We conduct literature studies of scientific articles, research journals, and books at national and international vessels. The search results identified 67 Indonesian medicinal plants used to treat symptoms of mental health disorders. The Zingiberaceae family is reported as the most medicinal plant that can potentially treat mental health disorders such as depression and anxiety. Several plants have been proven in preclinical research, but many still have not been studied and proven. Therefore, further research on Indonesian medicinal plants that can overcome mental health disorders must be carried out to provide knowledge and develop drugs for mental health disorders.
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治疗精神疾病的印尼印尼药用植物:焦虑和抑郁
心理健康疾病,尤其是焦虑症和抑郁症,目前正被广泛讨论。由于 COVID-19 的流行,2020 年患有焦虑症和抑郁症的人数大幅增加。这些精神疾病相当严重,亟待解决。印度尼西亚人世世代代都在日常生活中使用药用植物,其中之一就是治疗精神疾病的症状,如增强情绪和动力、镇静、克服抑郁、压力、焦虑和睡眠障碍。然而,目前还没有关于印尼药用植物治疗抑郁和焦虑等精神疾病的民族药理学的全面综述,也几乎没有科学证据支持这些植物的功效。本文回顾了用于治疗精神疾病的印尼药用植物,并回顾了这些植物的科学证据。我们对国内外的科学文章、研究期刊和书籍进行了文献研究。搜索结果发现了 67 种用于治疗精神疾病症状的印尼药用植物。据报道,最有可能治疗抑郁症和焦虑症等精神疾病的药用植物是姜科植物。有几种植物已在临床前研究中得到证实,但仍有许多植物尚未得到研究和证实。因此,必须进一步研究印尼可治疗精神疾病的药用植物,以提供知识和开发治疗精神疾病的药物。
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