Pranali Waghode, S. N. K. Rao G, Sanika Deshpande, Roja Rani Budha, R. R. Alavala, Surya Kovvasu
{"title":"Revolutionizing Cancer Treatment: Harnessing Cell-membrane Coated Nanoparticles for Precise Targeting and Therapy","authors":"Pranali Waghode, S. N. K. Rao G, Sanika Deshpande, Roja Rani Budha, R. R. Alavala, Surya Kovvasu","doi":"10.2174/0115733947295006240313045718","DOIUrl":null,"url":null,"abstract":"\n\nCancer is still a significant worldwide health issue that requires novel techniques for diagnosis\nand treatment. The complications associated with cancer are explored in this article, which also\nintroduces the novel concept of biomimetic nanoparticles as potential breakthrough in the fight\nagainst the disease. The introduction gives a general review of cancer, explaining its complexity and\nthe underlying mechanisms that give rise to it. Epidemiological findings highlight the impact of cancer\non the entire world and the most extensively found cancer driving the demand for innovative therapeutic\napproaches. A comprehensive review of the various cancer types follows with emphasis on\nunique traits, diagnostic methods, and treatment modalities, highlighting the variety of difficulties.\nAn achievable path forward for targeted cancer therapy is the emerging science of biomimetic nanoparticles.\nA thorough review of their many varieties and applications follows their introduction. These\nnanoparticles’ inventive nature, which was inspired by biological systems, is highlighted by the explanation\nof how they were synthesized. The focus is on biomimetic nanoparticles based on cancer cell\nmembranes as a novel means of medication administration and targeted therapy. Their use in the treatment\nof cancer is being investigated, with an emphasis on their potential to improve therapeutic efficacy\nand lessen side effects. Particularly noteworthy are the in-depth discussions of the unique difficulties\nencountered in treating lung, breast, prostate, colon, colorectal, ovarian, leukemia, lymphoma, melanoma,\npancreatic, bladder, oral, gastric, hepatic, perihilar cholangiocarcinoma, and cervical cancers. The\narticle also mentions the various challenges which may occur during this entire process.\n","PeriodicalId":503819,"journal":{"name":"Current Cancer Therapy Reviews","volume":" 9","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Cancer Therapy Reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/0115733947295006240313045718","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Cancer is still a significant worldwide health issue that requires novel techniques for diagnosis
and treatment. The complications associated with cancer are explored in this article, which also
introduces the novel concept of biomimetic nanoparticles as potential breakthrough in the fight
against the disease. The introduction gives a general review of cancer, explaining its complexity and
the underlying mechanisms that give rise to it. Epidemiological findings highlight the impact of cancer
on the entire world and the most extensively found cancer driving the demand for innovative therapeutic
approaches. A comprehensive review of the various cancer types follows with emphasis on
unique traits, diagnostic methods, and treatment modalities, highlighting the variety of difficulties.
An achievable path forward for targeted cancer therapy is the emerging science of biomimetic nanoparticles.
A thorough review of their many varieties and applications follows their introduction. These
nanoparticles’ inventive nature, which was inspired by biological systems, is highlighted by the explanation
of how they were synthesized. The focus is on biomimetic nanoparticles based on cancer cell
membranes as a novel means of medication administration and targeted therapy. Their use in the treatment
of cancer is being investigated, with an emphasis on their potential to improve therapeutic efficacy
and lessen side effects. Particularly noteworthy are the in-depth discussions of the unique difficulties
encountered in treating lung, breast, prostate, colon, colorectal, ovarian, leukemia, lymphoma, melanoma,
pancreatic, bladder, oral, gastric, hepatic, perihilar cholangiocarcinoma, and cervical cancers. The
article also mentions the various challenges which may occur during this entire process.