F. N. Karimah, Sugeng Mashudi, Saiful Nurhidayat, A. W. Azzarin, N. K. Amanah
{"title":"Assessment of anti-inflammatory of stem extract of Musa balbisiana in wound healing on rats (Rattus norvegicus)","authors":"F. N. Karimah, Sugeng Mashudi, Saiful Nurhidayat, A. W. Azzarin, N. K. Amanah","doi":"10.33024/minh.v7i1.206","DOIUrl":null,"url":null,"abstract":"Background: Balbisiana is a plant that contains flavonoids, which are antioxidants with high anti-inflammatory activity. This antioxidant activity can help the wound-healing process.\nPurpose: To determine the anti-inflammatory effect of balbisiana extract to help wound healing.\nMethod: The study used 15 rats, which were divided into five groups: a positive control group, a negative control group, a 10% balbisiana extract group, a 20% balbisiana extract group, and a 40% balbisiana extract group. Statistical analysis was performed using the Shapiro-Wilk test to test the normality of the distribution of continuous quantitative data. Levene's test was then used to assess the statistical homogeneity of variance between groups. Welch's One-Way ANOVA was used to analyze the data. Post-hoc analysis was performed using the Games-Howell test.\nResults: The results of the study showed that balbisiana extract had significant anti-inflammatory activity, especially at a concentration of 40%. This was demonstrated by the results of the study, which showed that rats treated with 40% balbisiana extract had significantly improved wound healing compared to the control groups.\nConclusion: This study shows that balbisiana extract has anti-inflammatory activity in helping the wound healing process.","PeriodicalId":18172,"journal":{"name":"Malahayati International Journal of Nursing and Health Science","volume":" 13","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Malahayati International Journal of Nursing and Health Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33024/minh.v7i1.206","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Balbisiana is a plant that contains flavonoids, which are antioxidants with high anti-inflammatory activity. This antioxidant activity can help the wound-healing process.
Purpose: To determine the anti-inflammatory effect of balbisiana extract to help wound healing.
Method: The study used 15 rats, which were divided into five groups: a positive control group, a negative control group, a 10% balbisiana extract group, a 20% balbisiana extract group, and a 40% balbisiana extract group. Statistical analysis was performed using the Shapiro-Wilk test to test the normality of the distribution of continuous quantitative data. Levene's test was then used to assess the statistical homogeneity of variance between groups. Welch's One-Way ANOVA was used to analyze the data. Post-hoc analysis was performed using the Games-Howell test.
Results: The results of the study showed that balbisiana extract had significant anti-inflammatory activity, especially at a concentration of 40%. This was demonstrated by the results of the study, which showed that rats treated with 40% balbisiana extract had significantly improved wound healing compared to the control groups.
Conclusion: This study shows that balbisiana extract has anti-inflammatory activity in helping the wound healing process.