Convergencia clínica: un caso excepcional de sarcoidosis y tuberculosis con múltiples manifestaciones orgánicas. Reporte de caso

Q3 Health Professions Revista Colombiana de Reumatologia Pub Date : 2025-01-01 DOI:10.1016/j.rcreu.2024.01.004

Néstor Correa-González , María Claudia Díaz , Keyla Jemihah Triana Ángel , María Daniela Polania , Natalia Remolina Murillo , Pilar Alarcón Robles

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Abstract

Introduction

The diagnosis of sarcoidosis is challenging, especially if the patient has concomitant infectious symptoms. Furthermore, the overlap of immune-mediated and infectious pathologies is not uncommon.

Objective

To report a rare case of association between tuberculosis and sarcoidosis.

Materials and methods

Description of the clinical characteristics of a patient who presented with sarcoidosis superimposed on tuberculosis.

Results

The case of a 29-year-old man with ocular, cutaneous, and systemic symptoms is described. Uveitis and chronic non-caseating granulomatous findings were diagnosed in the skin, lungs, and lymph nodes. Suspicion of tuberculosis led to positive molecular biology tests only in the lymph node biopsy. An overlap of sarcoidosis and tuberculosis was determined, and combined treatment with glucocorticoids and anti-tuberculosis agents was initiated, resulting in improvement of the patient.

Conclusions

Sarcoidosis and tuberculosis share characteristics from their aetiology to clinical manifestations, posing a challenge in clinical differentiation. Cases have been documented where both diseases overlap in the same patient.

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来源期刊

Revista Colombiana de Reumatologia Medicine-Rheumatology

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： The Colombian Journal of Rheumatology (Revista Colombiana de Reumatología) is the official organ of the Colombian Association of Rheumatology (Asociación Colombiana de Reumatología) and the Central American, Caribbean and Andean Association of Rheumatology (Asociación Centroamericana Caribe Andina de Reumatología) - ACCA. It was created in December 1993 with the purpose of disseminating scientific information derived from primary and secondary research and presenting cases coming from the practice of Rheumatology in Latin America. Since its foundation, the Journal has been characterized by its plurality with subjects of all rheumatic and osteomuscular pathologies, in the form of original articles, historical articles, economic evaluations, and articles of reflection and education in Medicine. It covers an extensive area of topics ranging from the broad spectrum of the clinical aspects of rheumatology and related areas in autoimmunity (both in pediatric and adult pathologies), to aspects of basic sciences. It is an academic tool for the different members of the academic and scientific community at their different levels of training, from undergraduate to post-doctoral degrees, managing to integrate all actors inter and trans disciplinarily. It is intended for rheumatologists, general internists, specialists in related areas, and general practitioners in the country and abroad. It has become an important space in the work of all rheumatologists from Central and South America.