Revista Colombiana de Reumatologia最新文献

Diseño e implementación de centros de cuidado clínico en espondiloartritis. Un modelo de atención y de enfermedad referente en patologías crónicas 脊椎关节炎临床护理中心的设计与实施。慢性疾病的护理和参考疾病模式

Q3 Health Professions

Revista Colombiana de Reumatologia

Pub Date : 2024-10-01 DOI: 10.1016/j.rcreu.2023.04.002

Introduction

Spondyloarthritis (SpA) is a musculoskeletal disease presenting with phenotypic clinical manifestations, integrating a set of interrelated inflammatory conditions, which share immunogenetic, epidemiological, and therapeutic characteristics.

Objective

to do a reflection exercise through the experience of designing and implementing a clinical care center for spondyloarthropathies, from the administrative and clinical perspective to the implications in decision making and impact on the different indicators related to efficiencies and safety of the services included in the model.

Results

In clinical practice, the reality of the care process in patients diagnosed with SpA represents an area of opportunity in multiple aspects. The fragmentation of clinical care and the heterogeneous flow of the patient in the care pathway, are associated with suboptimal and undesired clinical outcomes. Several aspects highlight the reality of patients with SpA in the national scenario, which -to a certain extent- could reflect what is observed in other Latin American countries. SpA represents a very significant burden for society and for individuals affected by this condition. Comprehensive assessment of the burden of disease from the perspective of the clinician and the patient is important, in order to support decisions related to treatment and comprehensive management of this condition. The improvement in health outcomes and the reduction in the cost of chronic inflammatory diseases, such as SpA, are the main advantages of implementing a care model in specialized centres integrating a multidisciplinary team.

Conclusion

This is an opportunity to include the perspective of individuals affected by this condition, seeking integration between an informed patient and a highly qualified multidisciplinary care team in the comprehensive management of patients with SpA.

导言软骨关节炎（Spondyloarthritis，SpA）是一种具有表型临床表现的肌肉骨骼疾病，它综合了一系列相互关联的炎症，具有共同的免疫遗传学、流行病学和治疗学特征。目标通过设计和实施脊柱关节病临床护理中心的经验进行反思，从行政和临床角度分析决策的影响，以及对该模式所含服务的效率和安全性相关不同指标的影响。临床护理的分散性和患者在护理路径中的异质性流动与不理想和不期望的临床结果有关。有几个方面凸显了国内 SpA 患者的实际情况，这在一定程度上反映了其他拉美国家的情况。SpA给社会和患者带来了沉重的负担。从临床医生和患者的角度对疾病负担进行全面评估非常重要，有助于做出治疗和综合管理该疾病的相关决定。结论：这是一个将受该疾病影响的个人视角纳入其中的机会，在对 SpA 患者的综合管理中，寻求知情患者与高素质的多学科护理团队之间的整合。

{"title":"Diseño e implementación de centros de cuidado clínico en espondiloartritis. Un modelo de atención y de enfermedad referente en patologías crónicas","authors":"","doi":"10.1016/j.rcreu.2023.04.002","DOIUrl":"10.1016/j.rcreu.2023.04.002","url":null,"abstract":"<div><h3>Introduction</h3><div>Spondyloarthritis (SpA) is a musculoskeletal disease presenting with phenotypic clinical manifestations, integrating a set of interrelated inflammatory conditions, which share immunogenetic, epidemiological, and therapeutic characteristics.</div></div><div><h3>Objective</h3><div>to do a reflection exercise through the experience of designing and implementing a clinical care center for spondyloarthropathies, from the administrative and clinical perspective to the implications in decision making and impact on the different indicators related to efficiencies and safety of the services included in the model.</div></div><div><h3>Results</h3><div>In clinical practice, the reality of the care process in patients diagnosed with SpA represents an area of opportunity in multiple aspects. The fragmentation of clinical care and the heterogeneous flow of the patient in the care pathway, are associated with suboptimal and undesired clinical outcomes. Several aspects highlight the reality of patients with SpA in the national scenario, which -to a certain extent- could reflect what is observed in other Latin American countries. SpA represents a very significant burden for society and for individuals affected by this condition. Comprehensive assessment of the burden of disease from the perspective of the clinician and the patient is important, in order to support decisions related to treatment and comprehensive management of this condition. The improvement in health outcomes and the reduction in the cost of chronic inflammatory diseases, such as SpA, are the main advantages of implementing a care model in specialized centres integrating a multidisciplinary team.</div></div><div><h3>Conclusion</h3><div>This is an opportunity to include the perspective of individuals affected by this condition, seeking integration between an informed patient and a highly qualified multidisciplinary care team in the comprehensive management of patients with SpA.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 511-516"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41323859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validación de la escala FACIT-fatiga en una muestra de población hispanohablante con artritis reumatoide 在一个患有类风湿性关节炎的西班牙语人口样本中验证FACIT疲劳量表

Q3 Health Professions

Revista Colombiana de Reumatologia

Pub Date : 2024-10-01 DOI: 10.1016/j.rcreu.2023.05.004

Introduction

Fatigue is a frequent symptom in patients with rheumatoid arthritis (RA). The Functional Assessment of Chronic illnesses Therapy-Fatigue (FACIT-F) is an instrument that assesses self-reported fatigue and was validated for measuring fatigue in RA.

Objective

The aim of this study was to validate the FACIT-F for use in Spanish-speaking RA patients.

Materials and methods

Cross-sectional, multicentre study. We included patients (n = 192) with RA diagnosis from two hospitals. Exploratory and confirmatory analyses were conducted. Construct validity and internal consistency were evaluated.

Results

FACIT-F showed high internal consistency (alpha = .87, omega = .93). Analysis of the main components showed a single factor, which explained 62% of the variance. The confirmatory factor analysis showed a satisfactory fit of the model. We found a correlation between FACIT–F, VAS fatigue (-.72 P < .001), and BRAF-MDQ (-.81 P < .001).

Conclusion

FACIT-F is a valid instrument with a high internal consistency for measuring fatigue in clinical practice and research in Spanish-speaking patients with RA.

导言疲劳是类风湿性关节炎（RA）患者经常出现的症状。慢性疾病治疗功能评估--疲劳（FACIT-F）是一种评估自我报告疲劳的工具，已被验证可用于测量 RA 患者的疲劳。我们纳入了两家医院的 RA 患者（n = 192）。进行了探索性和确认性分析。结果FACIT-F显示出较高的内部一致性（α=.87，ω=.93）。主成分分析表明只有一个因子，解释了 62% 的方差。确认性因子分析显示模型的拟合度令人满意。我们发现 FACIT-F、VAS 疲劳度（-.72 P <.001）和 BRAF-MDQ （-.81 P <.001）之间存在相关性。

{"title":"Validación de la escala FACIT-fatiga en una muestra de población hispanohablante con artritis reumatoide","authors":"","doi":"10.1016/j.rcreu.2023.05.004","DOIUrl":"10.1016/j.rcreu.2023.05.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Fatigue is a frequent symptom in patients with rheumatoid arthritis (RA). The Functional Assessment of Chronic illnesses Therapy-Fatigue (FACIT-F) is an instrument that assesses self-reported fatigue and was validated for measuring fatigue in RA.</div></div><div><h3>Objective</h3><div>The aim of this study was to validate the FACIT-F for use in Spanish-speaking RA patients.</div></div><div><h3>Materials and methods</h3><div>Cross-sectional, multicentre study. We included patients (n = 192) with RA diagnosis from two hospitals. Exploratory and confirmatory analyses were conducted. Construct validity and internal consistency were evaluated.</div></div><div><h3>Results</h3><div>FACIT-F showed high internal consistency (alpha = .87, omega = .93). Analysis of the main components showed a single factor, which explained 62% of the variance. The confirmatory factor analysis showed a satisfactory fit of the model. We found a correlation between FACIT–F, VAS fatigue (-.72 <em>P</em> < .001), and BRAF-MDQ (-.81 <em>P</em> < .001).</div></div><div><h3>Conclusion</h3><div>FACIT-F is a valid instrument with a high internal consistency for measuring fatigue in clinical practice and research in Spanish-speaking patients with RA.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 435-441"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49523844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Caracterización de los pacientes menores de 18 años con nefritis lúpica en el Hospital Pablo Tobón Uribe y en el Hospital San Vicente Fundación de la ciudad de Medellín, entre 2008 y 2017 2008 年至 2017 年间，麦德林市巴勃罗-托邦-乌里韦医院和圣维森特基金会医院中 18 岁以下狼疮肾炎患者的特征。

Q3 Health Professions

Revista Colombiana de Reumatologia

Pub Date : 2024-10-01 DOI: 10.1016/j.rcreu.2023.09.005

Introduction

The kidney is one of the organs frequently affected in systemic lupus erythematosus (40-60%); the manifestations are variable, from a silent pattern to the irreversible impairment of renal function.

Objetives

•
To characterize patients under 18 years of age with a diagnosis of lupus nephritis treated at the Pablo Tobón Uribe Hospital and San Vicente Fundación Hospital during the years 2006 to 2017.
•
Establish the frequency of lupus nephritis in patients diagnosed with childhood systemic lupus erythematosus.
•
Describe the general, sociodemographic, clinical and paraclinical characteristics, as well as histopathological characteristics, immunosuppressive treatment and complications such as chronic kidney disease, high blood pressure, need for renal replacement therapy and death in patients diagnosed with lupus nephritis.
•
Explore the association between lupus nephritis with a histological pattern defined as moderate or severe and chronic kidney disease, arterial hypertension, need for renal replacement therapy and death.

Materials and methods

Descriptive study with retrospective information in a group of patients under 18 years of age with a diagnosis of lupus nephritis, attended in two referral centres of the city of Medellin between 2008 and 2017. Clinical records of patients who met the inclusion criteria were reviewed.

Results

The median age was 13 years, with predominance in females. The majority had renal involvement at the time of diagnosis of lupus. Histological class IV was the most frequent (48%). Age under 10 years, absence of response to induction therapy, and histological class IV, were related to the development of chronic kidney disease (> 60 ml/min/1.73 m²).

Conclusions

Renal involvement was higher in this study. Age, class IV, and non-response to induction were associated with impaired renal function.

导言：肾脏是系统性红斑狼疮（40%-60%）中经常受累的器官之一；其表现多种多样，从无声无息的模式到不可逆转的肾功能损害，不一而足。-描述狼疮肾炎患者的一般、社会人口学、临床和辅助临床特征，以及组织病理学特征、免疫抑制治疗和并发症，如慢性肾病、高血压、需要肾脏替代治疗和死亡。-材料与方法对 2008 年至 2017 年间在麦德林市两家转诊中心就诊的一组 18 岁以下诊断为狼疮性肾炎的患者进行回顾性资料描述性研究。结果中位年龄为13岁，女性居多。大多数患者在确诊狼疮时肾脏已受累。组织学分级为IV级的患者最多（48%）。年龄不足 10 岁、对诱导治疗无反应、组织学分级 IV 级与慢性肾病（60 毫升/分钟/1.73 平方米）的发展有关。年龄、IV级和对诱导治疗无反应与肾功能受损有关。

{"title":"Caracterización de los pacientes menores de 18 años con nefritis lúpica en el Hospital Pablo Tobón Uribe y en el Hospital San Vicente Fundación de la ciudad de Medellín, entre 2008 y 2017","authors":"","doi":"10.1016/j.rcreu.2023.09.005","DOIUrl":"10.1016/j.rcreu.2023.09.005","url":null,"abstract":"<div><h3>Introduction</h3><div>The kidney is one of the organs frequently affected in systemic lupus erythematosus (40-60%); the manifestations are variable, from a silent pattern to the irreversible impairment of renal function.</div></div><div><h3>Objetives</h3><div><ul><li><span>•</span><span><div>To characterize patients under 18 years of age with a diagnosis of lupus nephritis treated at the Pablo Tobón Uribe Hospital and San Vicente Fundación Hospital during the years 2006 to 2017.</div></span></li><li><span>•</span><span><div>Establish the frequency of lupus nephritis in patients diagnosed with childhood systemic lupus erythematosus.</div></span></li><li><span>•</span><span><div>Describe the general, sociodemographic, clinical and paraclinical characteristics, as well as histopathological characteristics, immunosuppressive treatment and complications such as chronic kidney disease, high blood pressure, need for renal replacement therapy and death in patients diagnosed with lupus nephritis.</div></span></li><li><span>•</span><span><div>Explore the association between lupus nephritis with a histological pattern defined as moderate or severe and chronic kidney disease, arterial hypertension, need for renal replacement therapy and death.</div></span></li></ul></div></div><div><h3>Materials and methods</h3><div>Descriptive study with retrospective information in a group of patients under 18years of age with a diagnosis of lupus nephritis, attended in two referral centres of the city of Medellin between 2008 and 2017. Clinical records of patients who met the inclusion criteria were reviewed.</div></div><div><h3>Results</h3><div>The median age was 13 years, with predominance in females. The majority had renal involvement at the time of diagnosis of lupus. Histological classIV was the most frequent (48%). Age under 10years, absence of response to induction therapy, and histological classIV, were related to the development of chronic kidney disease (>60ml/min/1.73m<sup>2</sup>).</div></div><div><h3>Conclusions</h3><div>Renal involvement was higher in this study. Age, classIV, and non-response to induction were associated with impaired renal function.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 463-472"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139293049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comite Editorial online 编辑委员会在线

Q3 Health Professions

Revista Colombiana de Reumatologia

Pub Date : 2024-10-01 DOI: 10.1016/S0121-8123(24)00088-4

引用次数: 0

Growing up with juvenile idiopathic arthritis: Social issues 在幼年特发性关节炎中成长：社会问题

Q3 Health Professions

Revista Colombiana de Reumatologia

Pub Date : 2024-10-01 DOI: 10.1016/j.rcreu.2023.08.006

Introduction

Juvenile idiopathic arthritis is a chronic inflammatory condition interfering with daily activities, social integration, and school attendance in children because of pain and joint inflammation during disease flares. Online resources might help children with JIA improve their social interactions and enhance their knowledge about their disease and the available therapeutic strategies.

Objective

This study aims to reveal the social issues encountered by teenagers prone to JIA and determine their perception of the impact of social media on their daily life.

Material and methods

We conducted this study using inductive qualitative methods to describe the sociocultural perception and experience of adolescents with JIA aged between 8 and 16 years.

Results

Individual interviews were held with 22 adolescents diagnosed with JIA. Fifty-two percent felt like outcasts and rejected by their peers because of their illness. Most of the participants expressed a need for their friends to be informed about their JIA diagnosis. Twenty-two-point-seven percent stated that they played sports for more than 5 h a week. A total of 31.8% found their physical performance was not affected by their disease. Ninety-seven of the participants confirmed that they use social media on average 3 h a day. YouTube and Facebook were ranked respectively as the first and the second preferred platforms. Seventeen percent of the children viewed these platforms as positive and helpful in dealing with JIA, especially by taking their minds off the pain, dealing with the stress resulting from the lack of mobility, and facilitating interactions with others.

Conclusion

Social integration in children with JIA is still challenging. Social media is helpful in managing JIA and improving social interactions, and in gaining useful information.

导言青少年特发性关节炎是一种慢性炎症，由于疾病发作时的疼痛和关节炎症，会影响儿童的日常活动、社会融入和入学。本研究旨在揭示易患 JIA 的青少年所遇到的社会问题，并确定他们对社交媒体对其日常生活的影响的看法。材料和方法我们采用归纳定性方法进行了这项研究，以描述 8 至 16 岁 JIA 青少年的社会文化观念和经历。52%的受访者感觉自己是被遗弃者，因为自己的疾病而被同龄人排斥。大多数参与者表示需要让他们的朋友了解他们的JIA诊断。22.7%的人表示他们每周运动时间超过 5 小时。31.8%的人认为他们的运动表现没有受到疾病的影响。97%的参与者确认他们平均每天使用社交媒体 3 小时。YouTube 和 Facebook 分别被列为首选平台的第一位和第二位。17%的儿童认为这些平台对他们应对 JIA 有积极的帮助，尤其是可以让他们忘却疼痛、应对因行动不便而产生的压力以及促进与他人的交流。社交媒体有助于管理 JIA、改善社交互动和获取有用信息。

{"title":"Growing up with juvenile idiopathic arthritis: Social issues","authors":"","doi":"10.1016/j.rcreu.2023.08.006","DOIUrl":"10.1016/j.rcreu.2023.08.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Juvenile idiopathic arthritis is a chronic inflammatory condition interfering with daily activities, social integration, and school attendance in children because of pain and joint inflammation during disease flares. Online resources might help children with JIA improve their social interactions and enhance their knowledge about their disease and the available therapeutic strategies.</div></div><div><h3>Objective</h3><div>This study aims to reveal the social issues encountered by teenagers prone to JIA and determine their perception of the impact of social media on their daily life.</div></div><div><h3>Material and methods</h3><div>We conducted this study using inductive qualitative methods to describe the sociocultural perception and experience of adolescents with JIA aged between 8 and 16 years.</div></div><div><h3>Results</h3><div>Individual interviews were held with 22 adolescents diagnosed with JIA. Fifty-two percent felt like outcasts and rejected by their peers because of their illness. Most of the participants expressed a need for their friends to be informed about their JIA diagnosis. Twenty-two-point-seven percent stated that they played sports for more than 5h a week. A total of 31.8% found their physical performance was not affected by their disease. Ninety-seven of the participants confirmed that they use social media on average 3h a day. YouTube and Facebook were ranked respectively as the first and the second preferred platforms. Seventeen percent of the children viewed these platforms as positive and helpful in dealing with JIA, especially by taking their minds off the pain, dealing with the stress resulting from the lack of mobility, and facilitating interactions with others.</div></div><div><h3>Conclusion</h3><div>Social integration in children with JIA is still challenging. Social media is helpful in managing JIA and improving social interactions, and in gaining useful information.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 452-456"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139296411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hallazgos clínicos, de laboratorio y evolución en pacientes con síndrome autoinmune/autoinflamatorio inducido por adyuvantes (ASIA) 佐剂诱发自身免疫/自体发炎综合征（AIAIS）患者的临床和实验室检查结果及预后

Q3 Health Professions

Revista Colombiana de Reumatologia

Pub Date : 2024-10-01 DOI: 10.1016/j.rcreu.2023.09.008

Introduction and objective

Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) suggests that contact with different adjuvants such as silicones or aluminium used as excipient in some vaccines can cause the appearance of different symptomatology.

Materials and methods

A retrospective analysis of the clinical manifestations, laboratory parameters, treatment, and evolution of a case series of 13 patients with ASIA syndrome related to silicone implants and vaccines was performed.

Results

In 10 (77%) of the patients there was a history of silicone implants, in the rest of the patients there was a history of vaccination. The most frequent symptom in patients with silicone prostheses was Raynaud's phenomenon (72%), while in patients with a history of vaccination, arthralgias and myalgias were the most frequent symptoms. One patient met the criteria for primary Sjögren's syndrome while another patient had limited systemic sclerosis and associated Sjögren's syndrome. Most of the patients had elevated acute phase reactants (61%), while in the group of patients with a history of silicone prosthesis 60% presented positivity for antinuclear antibodies.

Conclusion

Raynaud's phenomenon and skeletal muscle symptoms were the most common manifestations in patients with breast prosthesis and vaccination history, respectively.

简介和目的佐剂诱发的自身免疫/自身炎症综合征（ASIA）表明，接触不同的佐剂（如硅酮或某些疫苗中用作赋形剂的铝）会导致出现不同的症状。材料和方法对 13 例与硅胶植入物和疫苗有关的 ASIA 综合征患者的临床表现、实验室指标、治疗和演变进行了回顾性分析。结果 10 例（77%）患者有硅胶植入史，其余患者有疫苗接种史。硅胶假体患者最常见的症状是雷诺现象（72%），而有疫苗接种史的患者最常见的症状是关节痛和肌痛。一名患者符合原发性斯约格伦综合征的标准，另一名患者则患有局限性系统性硬化症和相关的斯约格伦综合征。结论雷诺现象和骨骼肌症状分别是有乳房假体和疫苗接种史的患者最常见的表现。

{"title":"Hallazgos clínicos, de laboratorio y evolución en pacientes con síndrome autoinmune/autoinflamatorio inducido por adyuvantes (ASIA)","authors":"","doi":"10.1016/j.rcreu.2023.09.008","DOIUrl":"10.1016/j.rcreu.2023.09.008","url":null,"abstract":"<div><h3>Introduction and objective</h3><div>Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) suggests that contact with different adjuvants such as silicones or aluminium used as excipient in some vaccines can cause the appearance of different symptomatology.</div></div><div><h3>Materials and methods</h3><div>A retrospective analysis of the clinical manifestations, laboratory parameters, treatment, and evolution of a case series of 13 patients with ASIA syndrome related to silicone implants and vaccines was performed.</div></div><div><h3>Results</h3><div>In 10 (77%) of the patients there was a history of silicone implants, in the rest of the patients there was a history of vaccination. The most frequent symptom in patients with silicone prostheses was Raynaud's phenomenon (72%), while in patients with a history of vaccination, arthralgias and myalgias were the most frequent symptoms. One patient met the criteria for primary Sjögren's syndrome while another patient had limited systemic sclerosis and associated Sjögren's syndrome. Most of the patients had elevated acute phase reactants (61%), while in the group of patients with a history of silicone prosthesis 60% presented positivity for antinuclear antibodies.</div></div><div><h3>Conclusion</h3><div>Raynaud's phenomenon and skeletal muscle symptoms were the most common manifestations in patients with breast prosthesis and vaccination history, respectively.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 457-462"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139303182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A propósito de autoinmunidad y COVID-19 en pediatría 儿科自身免疫与 COVID-19

Q3 Health Professions

Revista Colombiana de Reumatologia

Pub Date : 2024-10-01 DOI: 10.1016/j.rcreu.2024.09.001

Adriana Diaz-Maldonado

引用次数: 0

Autoinmunidad en pacientes pediátricos de una región de Colombia, tras un pico de SARS-CoV-2 哥伦比亚某地区的儿科患者在 SARS-CoV-2 峰值之后出现自身免疫现象

Q3 Health Professions

Revista Colombiana de Reumatologia

Pub Date : 2024-10-01 DOI: 10.1016/j.rcreu.2023.08.001

Introduction

With the onset of the 2019 coronavirus pandemic, there was an increase in the number of reported cases of autoimmune manifestations in the midst of the disease and new cases of autoimmunity after infection.

Objective

To correlate the rate of positive tests of SARS-CoV-2 with the rate of new diagnoses of autoimmune disease in paediatric patients of the department of Huila (Colombia), between March 2020 and September 2021.

Methods

The socio-demographic characterization of the subjects diagnosed with autoimmune disease and of the cases of SARS-CoV-2 was performed; an analysis of the monthly trend of events was performed and a correlation model was applied between the rate of SARS-CoV-2 diagnosis and the rate of autoimmune diseases during the study period.

Results

A total of 94 cases of autoimmune disease were diagnosed, with an average age of 8.3 years, most were girls and belonged to the urban area and the subsidized regimen, and immune thrombocytopenic purpura was the most common diagnosis. In addition, 4,303 cases of SARS-CoV-2 were detected, mostly adolescents, from urban areas and the contributory system. Finally, it was evidenced that the highest rate of autoimmune disease was reported just after the highest peak of SARS-CoV-2.

Conclusions

This study did not show a statistical correlation between the rate of SARS-CoV-2 and the rate of diagnoses of autoimmune disease; however, it showed an enormous peak of autoimmunity after the highest peak of infection in paediatric patients of the department during the first eighteen months of the pandemic.

摘要: 随着2019年冠状病毒大流行的到来，在疾病期间报告的自身免疫表现病例和感染后新出现的自身免疫病例数量有所增加。方法对诊断为自身免疫性疾病的受试者和 SARS-CoV-2 病例进行社会人口学特征描述；对每月事件趋势进行分析，并在研究期间应用 SARS-CoV-2 诊断率与自身免疫性疾病发病率之间的相关模型。结果共诊断出 94 例自身免疫性疾病，平均年龄为 8.3 岁，大多数为女孩，属于城市地区和补贴方案，免疫性血小板减少性紫癜是最常见的诊断。此外，还发现了 4 303 例 SARS-CoV-2 病例，其中大部分是青少年，来自城市地区和补助系统。结论这项研究没有显示出 SARS-CoV-2 感染率与自身免疫性疾病诊断率之间存在统计学上的相关性；但是，它显示出在大流行的前 18 个月中，该部门的儿科病人在感染最高峰之后出现了一个巨大的自身免疫高峰。

{"title":"Autoinmunidad en pacientes pediátricos de una región de Colombia, tras un pico de SARS-CoV-2","authors":"","doi":"10.1016/j.rcreu.2023.08.001","DOIUrl":"10.1016/j.rcreu.2023.08.001","url":null,"abstract":"<div><h3>Introduction</h3><div>With the onset of the 2019 coronavirus pandemic, there was an increase in the number of reported cases of autoimmune manifestations in the midst of the disease and new cases of autoimmunity after infection.</div></div><div><h3>Objective</h3><div>To correlate the rate of positive tests of SARS-CoV-2 with the rate of new diagnoses of autoimmune disease in paediatric patients of the department of Huila (Colombia), between March 2020 and September 2021.</div></div><div><h3>Methods</h3><div>The socio-demographic characterization of the subjects diagnosed with autoimmune disease and of the cases of SARS-CoV-2 was performed; an analysis of the monthly trend of events was performed and a correlation model was applied between the rate of SARS-CoV-2 diagnosis and the rate of autoimmune diseases during the study period.</div></div><div><h3>Results</h3><div>A total of 94 cases of autoimmune disease were diagnosed, with an average age of 8.3years, most were girls and belonged to the urban area and the subsidized regimen, and immune thrombocytopenic purpura was the most common diagnosis. In addition, 4,303 cases of SARS-CoV-2 were detected, mostly adolescents, from urban areas and the contributory system. Finally, it was evidenced that the highest rate of autoimmune disease was reported just after the highest peak of SARS-CoV-2.</div></div><div><h3>Conclusions</h3><div>This study did not show a statistical correlation between the rate of SARS-CoV-2 and the rate of diagnoses of autoimmune disease; however, it showed an enormous peak of autoimmunity after the highest peak of infection in paediatric patients of the department during the first eighteen months of the pandemic.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 442-451"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139304262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluación de desenlaces clínicos en los pacientes con artritis reumatoide desde la perspectiva del paciente: revisión narrativa de la literatura 从患者角度评估类风湿关节炎患者的临床疗效：文献叙事回顾

Q3 Health Professions

Revista Colombiana de Reumatologia

Pub Date : 2024-10-01 DOI: 10.1016/j.rcreu.2023.08.007

Introduction

The evaluation of clinical outcomes in rheumatoid arthritis patients, including the patient's perspective, allows the inclusion of the patient's perspective in clinical decision-making using instruments designed for this purpose.

Objective

To identify and describe the instruments validated in Spanish to evaluate clinical outcomes in rheumatoid arthritis in daily clinical practice and from the patient's perspective, including disease activity, functionality, impact of the disease, adherence to treatment and quality of life.

Materials and methods

A review of the literature in various databases (PubMed, Scopus, Bireme, Scielo) was conducted e looking for questionnaires that evaluate clinical outcomes in rheumatoid arthritis patients, including those with a validated Spanish translation that allow self-assessment of the disease by the patient and clinical monitoring.

Results

Fifteen questionnaires were identified and selected that met the inclusion criteria. Four instruments were found that evaluate quality of life, three that evaluate functionality, four that evaluate disease impact, one that evaluate disease activity, and three that evaluate adherence to treatment.

Conclusion

Questionnaires and scales that evaluate rheumatoid arthritis allow a clinical approach to the evolution of the disease as perceived and reported by the patients, optimizing clinical follow up. Implementation of these tools in clinical decision making allows for an improvement in quality of care of patient with this condition.

目的确定并描述经西班牙文验证的用于评估类风湿关节炎患者在日常临床实践中的临床结果的工具，并从患者的角度进行评估，包括疾病活动、功能、疾病影响、治疗依从性和生活质量。材料与方法对各种数据库（PubMed、Scopus、Bireme、Scielo）中的文献进行了回顾，寻找评估类风湿性关节炎患者临床疗效的问卷，包括那些经过验证的西班牙语翻译，允许患者对疾病进行自我评估和临床监测的问卷。结论评估类风湿性关节炎的问卷和量表有助于临床了解患者感知和报告的疾病演变情况，优化临床随访。在临床决策中使用这些工具可以提高对该病患者的护理质量。

{"title":"Evaluación de desenlaces clínicos en los pacientes con artritis reumatoide desde la perspectiva del paciente: revisión narrativa de la literatura","authors":"","doi":"10.1016/j.rcreu.2023.08.007","DOIUrl":"10.1016/j.rcreu.2023.08.007","url":null,"abstract":"<div><h3>Introduction</h3><div>The evaluation of clinical outcomes in rheumatoid arthritis patients, including the patient's perspective, allows the inclusion of the patient's perspective in clinical decision-making using instruments designed for this purpose.</div></div><div><h3>Objective</h3><div>To identify and describe the instruments validated in Spanish to evaluate clinical outcomes in rheumatoid arthritis in daily clinical practice and from the patient's perspective, including disease activity, functionality, impact of the disease, adherence to treatment and quality of life.</div></div><div><h3>Materials and methods</h3><div>A review of the literature in various databases (PubMed, Scopus, Bireme, Scielo) was conducted e looking for questionnaires that evaluate clinical outcomes in rheumatoid arthritis patients, including those with a validated Spanish translation that allow self-assessment of the disease by the patient and clinical monitoring.</div></div><div><h3>Results</h3><div>Fifteen questionnaires were identified and selected that met the inclusion criteria. Four instruments were found that evaluate quality of life, three that evaluate functionality, four that evaluate disease impact, one that evaluate disease activity, and three that evaluate adherence to treatment.</div></div><div><h3>Conclusion</h3><div>Questionnaires and scales that evaluate rheumatoid arthritis allow a clinical approach to the evolution of the disease as perceived and reported by the patients, optimizing clinical follow up. Implementation of these tools in clinical decision making allows for an improvement in quality of care of patient with this condition.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 489-497"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135565146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inadequate sleep as a limiting factor in achieving remission in patients with rheumatoid arthritis 睡眠不足是类风湿关节炎患者缓解的限制因素

Q3 Health Professions

Revista Colombiana de Reumatologia

Pub Date : 2024-10-01 DOI: 10.1016/j.rcreu.2023.05.005

Introduction

Good sleep has a restorative effect at the cellular level and helps maintain the body's homeostasis.

Objectives

Given our clinical experiences, we propose that sleep quality should be evaluated in patients with rheumatoid arthritis. Poor sleep quality should be considered as a factor that may impact clinical outcomes in patients with rheumatoid arthritis.

Materials and methods

We researched medical literature on clinical and physiological pathways associated with sleep quality.

Results

There is evidence that interleukin-6 and tumor necrosis factor have a role in inflammatory and immune imbalance as well as in sleep disturbance in patients with rheumatoid arthritis, which leads to the chronic inflammatory process seen in these patients. Most patients with rheumatoid arthritis report sleep problems, be it insomnia or other complaints of non-refreshing sleep. Lack of sleep or poor sleep patterns in these patients further compromise their quality of life. In patients with RA, aetiologies such as restless leg syndrome (RLS), sleep apnoea syndrome, and Temporomandibular Joint Dysfunction (TMJ) syndromes might contribute to sleep disturbances. This lack of restful sleep might limit our goal, as treating physicians, to achieve remission states in these patients.

Conclusions

It is our opinion that sleep quality evaluation must be addressed, monitored, and treated as part of the management of patients with RA. Bad sleep adds an additional burden to disease activity in patients with RA, besides, it limits patients’ possibility of achieving disease remission.

导言良好的睡眠在细胞水平上具有恢复作用，有助于维持机体的平衡。目的根据临床经验，我们建议对类风湿性关节炎患者的睡眠质量进行评估。材料和方法我们研究了与睡眠质量相关的临床和生理途径的医学文献。结果有证据表明，白细胞介素-6 和肿瘤坏死因子在类风湿关节炎患者的炎症和免疫失衡以及睡眠障碍中发挥作用，从而导致这些患者出现慢性炎症过程。大多数类风湿性关节炎患者都有睡眠问题，无论是失眠还是其他睡眠不清爽的主诉。这些患者缺乏睡眠或睡眠模式不佳会进一步影响他们的生活质量。在类风湿性关节炎患者中，不宁腿综合征（RLS）、睡眠呼吸暂停综合征和颞下颌关节功能障碍（TMJ）综合征等病因都可能导致睡眠障碍。我们认为，睡眠质量评估必须作为 RA 患者管理的一部分来处理、监测和治疗。我们认为，睡眠质量评估必须作为 RA 患者管理的一部分来处理、监测和治疗。睡眠质量差不仅会增加 RA 患者疾病活动的负担，还会限制患者获得疾病缓解的可能性。

{"title":"Inadequate sleep as a limiting factor in achieving remission in patients with rheumatoid arthritis","authors":"","doi":"10.1016/j.rcreu.2023.05.005","DOIUrl":"10.1016/j.rcreu.2023.05.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Good sleep has a restorative effect at the cellular level and helps maintain the body's homeostasis.</div></div><div><h3>Objectives</h3><div>Given our clinical experiences, we propose that sleep quality should be evaluated in patients with rheumatoid arthritis. Poor sleep quality should be considered as a factor that may impact clinical outcomes in patients with rheumatoid arthritis.</div></div><div><h3>Materials and methods</h3><div>We researched medical literature on clinical and physiological pathways associated with sleep quality.</div></div><div><h3>Results</h3><div>There is evidence that interleukin-6 and tumor necrosis factor have a role in inflammatory and immune imbalance as well as in sleep disturbance in patients with rheumatoid arthritis, which leads to the chronic inflammatory process seen in these patients. Most patients with rheumatoid arthritis report sleep problems, be it insomnia or other complaints of non-refreshing sleep. Lack of sleep or poor sleep patterns in these patients further compromise their quality of life. In patients with RA, aetiologies such as restless leg syndrome (RLS), sleep apnoea syndrome, and Temporomandibular Joint Dysfunction (TMJ) syndromes might contribute to sleep disturbances. This lack of restful sleep might limit our goal, as treating physicians, to achieve remission states in these patients.</div></div><div><h3>Conclusions</h3><div>It is our opinion that sleep quality evaluation must be addressed, monitored, and treated as part of the management of patients with RA. Bad sleep adds an additional burden to disease activity in patients with RA, besides, it limits patients’ possibility of achieving disease remission.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 517-522"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41701564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0