STATINS IN THE TREATMENT OF PATIENTS WITH PERIPHERAL ARTERY DISEASES: STRATEGY AND TACTICS OF APPOINTMENT

Vrach Pub Date : 2024-03-01 DOI:10.29296/25877305-2024-03-03
E. Paranina, E. Krivoshchekov, P. Paranin
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Abstract

The article presents a review of the literature on the relationship of peripheral artery diseases and cardiovascular complications. According to modern concepts, peripheral artery diseases are classified as markers of very high cardiovascular risk. The most important aspect of the therapy of patients in this category, in addition to correcting specific symptoms of vascular lesions of the lower extremities, is to reduce the risk of developing cardiovascular diseases and their prevention, and treatment of patients in this category should be carried out in accordance with the recommendations for secondary prevention of cardiovascular complications, the most important part of which is the control of serum lipids. Statins are the most widely used class of drugs for the correction of hypercholesterolemia, but the frequency of their appointment as a strategically important class of drugs to prevent the development of atherosclerotic cardiovascular complications in high- and very high-risk individuals in the Russian Federation, as in other countries, remains low. The basic principles of lipid-lowering therapy in patients with peripheral artery diseases are described: strategies, goals and issues of therapy control.
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他汀类药物治疗外周动脉疾病患者:任命的战略和战术
文章回顾了有关外周动脉疾病与心血管并发症关系的文献。根据现代概念,外周动脉疾病被归类为心血管风险极高的标志。对这类患者的治疗,除了纠正下肢血管病变的特殊症状外,最重要的是降低罹患心血管疾病的风险和预防心血管疾病,对这类患者的治疗应根据心血管并发症二级预防的建议进行,其中最重要的部分是控制血清脂质。他汀类药物是治疗高胆固醇血症使用最广泛的一类药物,但与其他国家一样,在俄罗斯联邦,他汀类药物作为预防高危和极高危人群发生动脉粥样硬化性心血管并发症的一类重要战略药物,其使用频率仍然很低。本文介绍了外周动脉疾病患者降脂治疗的基本原则:策略、目标和治疗控制问题。
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