COVID-19 AND CLINICAL AND IMMUNOLOGICAL ASPECTS OF THE ORAL CAVITY IN WOMEN

Kamalova Dilafruz Danyarovna, Norkhujayeva Charoskhon
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Abstract

The study included 254 Covid-19 positive patients, from which 105 eligible patients were selected. The aim of the study was to determine the damage to the oral cavity in various degrees of severity of coronovirus infection, for early prediction of the clinical course of COVID-19 by using modern methods for studying local immune and inflammatory responses of the oral mucosa. During the study, the state of the oral cavity, laboratory data, including the determination of the level of IgA and IL-17, were studied, as well as bacteriological culture was carried out. During the study, an oral manifest was determined, indicating a high expression of ACE-2 receptors in the oral cavity, an inverse correlation with the clinical course of the disease and the state of the oral cavity, a complete blood count is less informative compared to determining the level of IgA and IL-17.
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covid-19与女性口腔的临床和免疫学问题
该研究包括254名Covid-19阳性患者,从中筛选出105名符合条件的患者。研究的目的是确定不同严重程度冠状病毒感染对口腔造成的损害,通过使用现代方法研究口腔黏膜的局部免疫和炎症反应,及早预测 COVID-19 的临床病程。研究期间,研究了口腔状况、实验室数据,包括 IgA 和 IL-17 水平的测定,并进行了细菌培养。研究期间,确定了口腔表现,表明 ACE-2 受体在口腔中高表达,与疾病的临床过程和口腔状态呈反相关,与确定 IgA 和 IL-17 水平相比,全血细胞计数的信息量较少。
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