ASPECTS CLINIQUES ET EVOLUTIFS DU CHOC SEPTIQUE EN REANIMATION DU CHU ANDOHATAPENAKA

Abstract

Introduction: Septic shock is a major problem in intensive care units because it is responsible for high mortality. We aim to describe septic shocks clinical, bacteriological, therapeutic, and outcome aspects in the Intensive Care Department of Andohatapenaka University Hospital. Methods: This is a 30-month retrospective descriptive study of patients admitted with septic shock to the intensive care unit of CHU Andohatapenaka. The parameters studied were sociodemographic data, clinical parameters, bacteriological parameters, and evolutionary outcomes. Results: The incidence of septic shock was 9.5%. The mean age was 59±15 years. Male predominance was 65.8%, with a sex ratio of 1.9. Hypertension was the main comorbidity (64.3%). Disturbed consciousness was the most common reason for admission (41.5%). Polypnoea was found in 92.7% of patients. Pulmonary infection was predominant in 78.1% of cases. In this study, 34.2% had undergone bacteriological sampling. Kochs bacillus (9.7%) and Gram-negative bacilli (12.2%) predominated among the germs found. All patients received vascular filling, vasopressors, oxygen therapy, and antibiotic treatment. In this study, 39% of patients received mechanical ventilation. The mortality rate was 73.1%. Conclusion: Septic shock is still a real public health problem. It is the leading cause of death in intensive care. A further study will be necessary to determine the predictive factors of septic shock to improve management.