Sexual Dysfunctions Among Female Major Depressive Disorder Patients of Reproductive Age

Rezwana Habiba, Sayed Sharif-ul-Alam, Md. Jasim Uddin, Romendra Kumar Singha, Md. Abdullah Sayed, A. R. Chowdhury
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Abstract

Background: Depression, a pervasive public health issue, is associated with substantial morbidity and mortality. Existing literature suggests a connection between depression and female sexual dysfunction, impacting the overall quality of life. Recognizing the prevalence of sexual dysfunction in Major Depressive Disorder (MDD) patients becomes crucial for holistic patient care. Objective: This cross-sectional observational study, conducted at Sylhet MAG Osmani Medical College Hospital from September 2018 to August 2020, aimed to assess the patterns and frequencies of sexual dysfunction in female MDD patients of reproductive age. The primary objectives included evaluating the correlation between the severity of depression and sexual dysfunction, as well as exploring the association between sexual dysfunction and socio-demographic variables. Method: Sixty-eight married, reproductive-age females diagnosed with MDD were included. Diagnosis followed DSM-5 criteria, with severity assessed using the Bangla version of the Depression Anxiety and Stress Scale (DASS-21) and sexual dysfunction evaluated via the Female Sexual Function Index (FSFI) scale. Statistical analyses employed Chi-square tests and Pearson’s correlation coefficient tests. Results: Of the participants, 77.9% experienced sexual dysfunction, with 41.2% exhibiting extremely severe depression. Dysfunction in desire (72.1%), arousal (67%), and satisfaction (54.4%) were prevalent, while 51.5% reported lubrication difficulties. Dysfunction in orgasm (44.1%) and pain (45.6%) were less frequent. A significant correlation was observed between female sexual dysfunction and depression severity (p=<0.001), while no statistically significant correlation was found between the duration of MDD and sexual dysfunction (p=0.122). Conclusion: This study underscores a high prevalence of sexual dysfunction in female MDD patients, emphasizing the necessity of routine inquiry into sexual health in the clinical management ...........
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育龄女性重度抑郁症患者的性功能障碍
背景:抑郁症是一个普遍存在的公共健康问题,与大量的发病率和死亡率有关。现有文献表明,抑郁症与女性性功能障碍之间存在联系,会影响整体生活质量。认识到重度抑郁障碍(MDD)患者中性功能障碍的普遍性对于患者的整体护理至关重要。研究目的这项横断面观察性研究于 2018 年 9 月至 2020 年 8 月在锡尔赫特 MAG Osmani 医学院医院进行,旨在评估育龄期女性 MDD 患者性功能障碍的模式和频率。主要目标包括评估抑郁症严重程度与性功能障碍之间的相关性,以及探讨性功能障碍与社会人口学变量之间的关联。研究方法共纳入 68 名被诊断为 MDD 的已婚育龄女性。诊断遵循 DSM-5 标准,严重程度采用孟加拉版抑郁、焦虑和压力量表(DASS-21)进行评估,性功能障碍采用女性性功能指数量表(FSFI)进行评估。统计分析采用了卡方检验和皮尔逊相关系数检验。结果显示77.9% 的参与者出现性功能障碍,其中 41.2% 的参与者表现出极其严重的抑郁。性欲障碍(72.1%)、性唤起障碍(67%)和性满足障碍(54.4%)普遍存在,51.5%的人报告称润滑困难。性高潮(44.1%)和疼痛(45.6%)功能障碍的发生率较低。女性性功能障碍与抑郁症严重程度之间存在明显相关性(p=<0.001),而多发性抑郁症持续时间与性功能障碍之间没有统计学意义上的明显相关性(p=0.122)。结论本研究强调了性功能障碍在女性 MDD 患者中的高发率,强调了在临床管理中对性健康进行常规调查的必要性 ...........
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