ASSOCIATION OF EUTHYROID TYPE 2 DIABETES MELLITUS WITH HEMOGLOBIN AND SERUM BILIRUBIN LEVELS RELATING TO GLYCEMIC CONTROL - A RETROSPECTIVE STUDY

Abstract

Background: Diabetes, along with its comorbidities, may increase the risk of anaemia by lowering iron absorption. In diabetic patients, thyroid illness was 14.7% prevalent. In 13% of T2DM patients, subclinical hypothyroidism was the most common thyroid condition. Diabetes glucose metabolism may be impacted by thyroid dysfunction, and variations in blood TSH have been linked to variations in glycatedhaemoglobin. Methodology: Retrospective study analysis of euthyroid type 2 diabetic patients who had attended the OPD in the department of General Medicine. The hospital records (case history from MRD) were used as the sources of information by following proper procedure in obtaining the same. Collection of data for a period of four years with Type 2 diabetes (FBS>126) and who did not possess any obvious clinical manifestations of thyroid disease was included for the study group. Results: PBS, HbA1C, LDL, TSH are highly significant with Fasting blood sugar with(p=0.00). FBS, RBC are highly significant with HbA1C (p=0.00). Uric acid, cholesterol,directbilirubin,haemoglobinishighlysignificantwithbilirubin(p=0.00).whereascholesterol, total billirubin are highly significant with haemoglobin (p=0.00). Hb showedpositive association with FT4. TAG, VLDL, Globulin showed negative association with FBS.HbisnegativelyassociatedwithTotalbilirubin.Cholesterolexhibitsstrongnegativeassociation with Hemoglobin (HbA1c ≥7). TSHwere associated with FBS. Direct bilirubinexhibits positive association with FBS and TotalCholesterol(HbA1c ≤7). Conclusion: Our study results outcome could be concluded that the thyroid status, haemoglobinandCBCcouldbeusefultoolforT2DMpatients.