PHYSICOCHEMICAL ANALYSIS OF SIDDHA POLY-HERBAL FORMULATION NELLIMULLI ILAGAM

C. Poongkothai, K. Vennila, M. M. Sundaram, R. Meenakumari
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Abstract

Introduction: The Siddha system is an ancient, holistic system. The medicine in this system is prepared from raw materials of herbs, metals, minerals and animal products. In recent years, considerable research has focused on validation and standardisation aspects. Nellimulli ilagam is a polyherbal Siddha formulation used to manage Veluppu noi. Aim: To study the physicochemical analysis of Nellimulli ilagam. Methods: Standardization parameters such as organoleptic characteristics, physicochemical analysis, test for aflatoxins, pesticide residues, specific pathogens, and heavy metal analysis were carried out as per PLIM guidelines. Results: The results obtained from the trial drug Nellimulli ilagam study show that it has a dark, brownish-coloured semi-solid texture with a strong characteristic odour and is non-free-flowing. Physicochemical analysis reveals that pH was 7.2, total ash value was 10±0.4 and acid insoluble ash value was 0.02±0.004. Loss on drying at 105 0C is 8.4±0.9. The test for aflatoxins and pesticide residues showed negative results. Test for microbial contamination and specific pathogen shows absent. Test for heavy metals shows below the limit of quantification (BLQ).
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Siddha 多草药配方 Nellimulli ilagam 的理化分析
简介释迦疗法是一种古老的整体疗法。该体系中的药物由草药、金属、矿物质和动物产品等原材料配制而成。近年来,大量研究集中在验证和标准化方面。Nellimulli ilagam 是一种用于治疗 Veluppu noi 的多草药 Siddha 配方。目的:研究 Nellimulli ilagam 的理化分析。方法:根据 PLIM 准则,对感官特征、理化分析、黄曲霉毒素、农药残留、特定病原体和重金属分析等标准化参数进行检测。结果:对试验药物 Nellimulli ilagam 的研究结果表明,它呈深褐色半固体质地,有强烈的特殊气味,不流动。理化分析表明,pH 值为 7.2,总灰分值为 10±0.4,酸不溶性灰分值为 0.02±0.004。105 0C 下的干燥损失为 8.4±0.9。黄曲霉毒素和农药残留检测结果为阴性。微生物污染和特定病原体检测结果为零。重金属检测结果低于定量限(BLQ)。
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