Conservative management of tubercular intestinal obstruction with antitubercular drugs and steroid

Dr Jayesh Kalbhande
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Abstract

Objective: Tubercular intestinal obstruction is a challenging condition often necessitating surgical intervention. This case study aims to evaluate the effectiveness of conservative management, including antitubercular therapy, short-course steroids, and dietary modifications, in resolving acute and complete intestinal obstruction caused by tuberculosis. Case Description: A 17-year-old malnourished male presented with acute abdominal pain, vomiting, and constipation. Imaging revealed mid-ileal intestinal obstruction due to tuberculosis. Conservative management, involving intravenous antibiotics, nasogastric decompression, steroids, and antitubercular treatment, led to gradual resolution. The patient experienced recurrent partial obstruction episodes, each managed conservatively with antibiotics, steroids, and dietary adjustments. A slow transition from liquid to solid diet accompanied recovery. After a year of treatment, the patient achieved recovery with weight gain. Conclusion: Tubercular intestinal obstruction, challenging to treat medically, often requires surgery. However, this case demonstrates the successful outcome through a comprehensive conservative approach. The inclusion of steroids alongside antitubercular treatment played a crucial role. Additionally, a cautious transition from liquid to solid diet post-resolution proved effective in preventing recurrence. Conservative management, when tailored to the patient's nutritional needs and disease course, can lead to favorable outcomes in tubercular intestinal obstruction.
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使用抗结核药物和类固醇对结核性肠梗阻进行保守治疗
目的:结核性肠梗阻是一种具有挑战性的疾病,通常需要进行手术治疗。本病例研究旨在评估保守治疗(包括抗结核治疗、短期类固醇治疗和饮食调整)在解决结核病引起的急性完全性肠梗阻方面的效果。病例描述一名 17 岁营养不良的男性因急性腹痛、呕吐和便秘就诊。影像学检查显示,他的肠道因结核病而中段梗阻。保守治疗包括静脉注射抗生素、鼻胃减压、类固醇和抗结核治疗,病情逐渐缓解。患者的部分肠梗阻反复发作,每次都采用抗生素、类固醇和饮食调整等保守治疗。在康复过程中,患者的饮食从流质食物慢慢过渡到固体食物。经过一年的治疗,患者的病情得到恢复,体重也有所增加。结论结核性肠梗阻的药物治疗具有挑战性,通常需要手术治疗。然而,本病例展示了综合保守治疗的成功结果。在抗结核治疗的同时使用类固醇起了关键作用。此外,在治疗后从流质饮食谨慎过渡到固体饮食,也有效地防止了复发。根据患者的营养需求和病程采取保守治疗,可为结核性肠梗阻患者带来良好的治疗效果。
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