Cytotoxic evaluation of curcumin and quercetin in MCF-7 cell lines

Devi Senthil, Venkateswaran Velliyagounder, Lakshmi Kanakaraj
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Abstract

Cytotoxic evaluation of Curcumin and Quercetin in MCF-7 cell lines was performed to assess their potential anticancer activity. MCF-7 is a widely used breast cancer cell line, and evaluating the cytotoxic effects of the compounds on these cells can provide valuable information about their potential as an anticancer agent. Curcumin, a naturally occurring compound found in turmeric, has been extensively studied for its potential anticancer properties, including its effects on MCF-7 cell lines. MCF-7 cells are commonly used as a model for studying breast cancer. Quercetin, a flavonoid found in various fruits, vegetables, and plant-based foods, has also been studied for its potential anticancer effects, including its effects on MCF-7 cell lines. The combination of curcumin and quercetin has been investigated for its potential synergistic effects on MCF-7 cell lines, aiming to enhance the anticancer activity of both compounds. The synergistic effects observed in the combination of curcumin and quercetin on MCF-7 cells suggests that the compounds may act through complementary mechanisms, enhancing their individual anticancer activities.
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姜黄素和槲皮素在 MCF-7 细胞系中的细胞毒性评估
我们对姜黄素和槲皮素在 MCF-7 细胞系中的细胞毒性进行了评估,以评估它们潜在的抗癌活性。MCF-7 是一种广泛使用的乳腺癌细胞系,评估化合物对这些细胞的细胞毒性作用可以为了解它们作为抗癌剂的潜力提供有价值的信息。姜黄素是姜黄中的一种天然化合物,其潜在的抗癌特性已被广泛研究,包括对 MCF-7 细胞系的影响。MCF-7 细胞通常被用作研究乳腺癌的模型。槲皮素是一种存在于各种水果、蔬菜和植物性食品中的类黄酮,其潜在的抗癌作用也已得到研究,包括对 MCF-7 细胞系的作用。我们研究了姜黄素和槲皮素的组合对 MCF-7 细胞系的潜在协同作用,目的是增强这两种化合物的抗癌活性。姜黄素和槲皮素联合使用对 MCF-7 细胞产生的协同效应表明,这两种化合物可能通过互补机制发挥作用,从而增强各自的抗癌活性。
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