An Insight into Herbal Interventions for Breast Cancer: A Comprehensive Review

Abstract

New therapies for life-threatening ailments like breast carcinoma are urgently required to relieve the ever-increasing burden of the mortality associated with it. The very specific feature associated with life-giving natural products is their lesser toxicity concerning existing strategies viz chemotherapy or adjuvant modalities. In our review, we have tried to compile the existing data on exploring herbal extracts and bio-actives through various in vitro and in vivo techniques. An attempt has been made to accumulate data for a scrupulous literature review retrieved via pertinent keywords in authentic records. Web of Science, Scopus, and Science Direct. The major keywords included herbal extract, in vitro, anticancer, and metastasis. A comprehensive exploration unveiled an imperative role against malignancies of various tissues, but we focussed on breast cancer cell lines. Still, extensive reports on herbal alternatives and their bio-active mechanism are highly implicated in tapping their potential as standardized regimens. Scientific evidence, correlations, and proper safety data may substantiate interventions in cancer therapy.