Application of logistic regression model on the spread of malaria infection in Calabar municipality (A case study of university of Calabar teaching hospital)

Deedumbari Charles Gboh-Igbara, Bassey Edet Effiong, Sebastian Stephen Akpan, Ugbe Thomas Adidaumbe, Enang Ekaette Inyang, Christian Elendu Onwuke, Joy Uket Ogum, Nja Egom Mbe
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Abstract

Background: The malaria disease is the outcome of the interaction among three elements which includes; man, mosquito and the parasite. The intensity of the disease is being regulated by the physical and socio-economic determinant in the area which interact with these elements. The physical conditions of the region determine the growth and proliferation of mosquito and parasite, while the socio-economic conditions of the people determine the distribution of mosquito and parasites. This piece of research work has been devoted to the study of vector species (Plasmodium), spatial-temporal incidence pattern of malaria i.e parasite load, physical and socio-economic determinants responsible for the spread of mosquito and parasites, control measures and risk factor assessment. The favourable explanatory variables considered in the prediction of malaria prevalence such as age group, gender, blood group and genotype presents suitable conditions to determine the validity of malaria prevalence across the metropolis which as well substantially contributed and facilitate the growth and diffusion of malarial incidence in Calabar Municipality. The data obtained was initially entered in Microsoft Excel (2016) and checked for errors after which it was exported to IBM SPSS Statistics 23 software for logistic regression analysis. The metropolis records high incidence of malaria. The predominant parasite plasmodium falciparum is considered vital for causing considerable morbidity and mortality in the area. From our analysis, it is observed that fifty nine of our patients were malaria negative and one hundred and one patients were malaria positive. The model predicted in respect to gender that seventy four percent of female population were malaria positive likewise the male gender predicted at eighty percent to be malaria positive.
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卡拉巴尔市疟疾感染传播的逻辑回归模型应用(卡拉巴尔大学教学医院案例研究)
背景:疟疾是人、蚊子和寄生虫这三个要素相互作用的结果。疾病的严重程度受该地区的自然条件和社会经济决定因素的影响,而这些因素又与这些因素相互作用。该地区的自然条件决定了蚊子和寄生虫的生长和繁殖,而人们的社会经济条件则决定了蚊子和寄生虫的分布。这项研究工作致力于研究病媒物种(疟原虫)、疟疾的时空发病模式(即寄生虫量)、蚊虫和寄生虫传播的自然和社会经济决定因素、控制措施和风险因素评估。在预测疟疾发病率时考虑的有利解释变量,如年龄组、性别、血型和基因型,为确定整个城市疟疾发病率的有效性提供了合适的条件,同时也大大促进和推动了卡拉巴尔市疟疾发病率的增长和扩散。获得的数据最初输入 Microsoft Excel(2016),检查无误后导出到 IBM SPSS Statistics 23 软件中进行逻辑回归分析。该市疟疾发病率较高。主要寄生虫恶性疟原虫被认为是造成该地区大量发病和死亡的重要原因。从我们的分析中可以看出,59 名患者为疟疾阴性,101 名患者为疟疾阳性。该模型根据性别预测,74% 的女性为疟疾阳性,而男性则有 80% 为疟疾阳性。
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