Initial evaluation of the application of autologous protein gel in the treatment of extensive skin loss wounds

Quang Tri Le, H. Phan, Thi Thanh Tam Vu, Gia Huy Truong, Nguyen Nhu Hieu Tran, Thi Dieu Thuan Hoang, Le Bao Ha Tran, Minh Quan To, Thi Ngoc My Nguyen, Nguyen Vu Doan
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Abstract

Objective: Develop a process and evaluate the effects of local treatment with protein gel on the patient’s skin graft wound. Subjects and methods: The case series study reported the results of treating skin loss wounds with protein gel application on 5 patients at the Department of Orthopedics and Traumatology - 7A Military Hospital from August 2023 to November 2023. Results: At the time of removing the skin graft bandage (day 7), a very good adhesion rate of the skin graft to the graft base was recorded (from 92-97%). After 2 weeks of transplantation, the graft skin adhesion rate reached 97-100%. By 4 weeks after transplantation, the grafted skin adhered 100% to the graft base in all 5 patients and all patients reported good results after skin grafting. Conclusion: The use of protein gel in the skin grafting process increases the adhesion of the grafted skin, reduces pain, reduces exudate at the wound, and increases the survival rate of the grafted skin.
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应用自体蛋白凝胶治疗大面积皮肤缺损伤口的初步评估
目标:开发一种程序,并评估使用蛋白凝胶对患者植皮伤口进行局部治疗的效果。研究对象和方法:该病例系列研究报告了 2023 年 8 月至 2023 年 11 月期间在 7A 军医院骨科和创伤科对 5 名患者应用蛋白凝胶治疗皮肤缺损伤口的结果。结果在拆除植皮绷带时(第 7 天),植皮与植皮基底的粘附率非常高(92%-97%)。移植 2 周后,移植皮肤的粘附率达到 97%-100%。移植 4 周后,5 名患者的移植皮肤与移植基底的粘附率均达到 100%,所有患者均表示植皮后效果良好。结论在植皮过程中使用蛋白凝胶可增加移植皮肤的粘附性,减轻疼痛,减少伤口处的渗出,提高移植皮肤的存活率。
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