Exploring the Impact of Treating Functional Constipation on Headache Episodes in Children Suffering from Migraine

Afshin Fayyazi, Maryam Shirmohamadi, A. Soltanian, H. Bazmamoun
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Abstract

Background: Migraine and functional constipation are prevalent chronic conditions among children, with many children suffering from migraines also experiencing functional constipation. Objectives: This study aims to investigate the impact of constipation treatment on headaches in children with migraines. Methods: This clinical trial involved 32 children aged 4 to 15 years, all diagnosed with both migraine and functional constipation. They were randomly divided into two groups: an intervention group and a control group, each comprising an equal number of participants. In the intervention group, both migraine and constipation were treated concurrently, whereas in the control group, only migraine was addressed. The outcomes of the two groups were then monitored and compared. Results: After the treatment, the intervention group experienced a significant reduction in the average number of monthly headache attacks (3 ± 2.4) compared to the control group (7.1 ± 6.9) with a P-value of 0.016. The average duration of each headache attack was shorter in the intervention group (2.3 ± 4.8 hours) compared to the control group (2.9 ± 4.2 hours), although this difference was not statistically significant. Parental satisfaction with the treatment was higher in the intervention group than in the control group, but this difference also lacked statistical significance. Constipation treatment was successful in all children in the study. Conclusions: The study's findings indicate that treating constipation in children with both migraine and functional constipation significantly reduces the frequency of headache attacks. However, it does not have a significant impact on the duration of headache attacks or on parental satisfaction with the treatment.
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探索治疗功能性便秘对偏头痛儿童头痛发作的影响
背景:偏头痛和功能性便秘是儿童中普遍存在的慢性疾病,许多患有偏头痛的儿童还伴有功能性便秘。研究目的本研究旨在探讨便秘治疗对偏头痛儿童头痛的影响。研究方法这项临床试验涉及 32 名 4 至 15 岁的儿童,他们均被诊断患有偏头痛和功能性便秘。他们被随机分为两组:干预组和对照组,每组人数相等。干预组同时治疗偏头痛和便秘,而对照组只治疗偏头痛。然后对两组的结果进行监测和比较。结果:治疗后,干预组每月头痛发作的平均次数(3±2.4 次)比对照组(7.1±6.9 次)显著减少,P 值为 0.016。干预组每次头痛发作的平均持续时间(2.3 ± 4.8 小时)比对照组(2.9 ± 4.2 小时)短,但这一差异在统计学上并不显著。干预组家长对治疗的满意度高于对照组,但这一差异也没有统计学意义。研究中所有儿童的便秘治疗都取得了成功。结论:研究结果表明,对患有偏头痛和功能性便秘的儿童进行便秘治疗可显著降低头痛发作的频率。但是,这对头痛发作的持续时间和家长对治疗的满意度并无明显影响。
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