Surface modification of Ti6Al4V alloy: A case study on anti‐Streptococcus mutans

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-02-23 DOI:10.1002/vjch.202300171
L. T. Nguyen, Tien A. Nguyen, Kwangsoo No, Tuan D. Phan
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Abstract

This study aims to improve the antibacterial effectiveness against Streptococcus mutans (S. mutans) of Ti6Al4V alloy by employing functional Ag coating on the alloy's surface. In this study, Ag coating was prepared on Ti6Al4V surface via RF magnetron sputtering, then investigated characteristics and anti‐S. mutans properties of the modified surface's alloy before and after immersing in simulated body fluid (SBF) solution for one month. Data showed that the two coatings inhibited the development of S. mutans colony‐forming units (CFU) at an incubation time until seven days. This study provides a research foundation for further development of surface modification of Ti6Al4V alloy for dental implants to meet the demand of reducing peri‐implant diseases caused by bacteria.
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Ti6Al4V 合金的表面改性:抗变异链球菌案例研究
本研究旨在通过在 Ti6Al4V 合金表面使用功能性 Ag 涂层来提高其对变异链球菌(S. mutans)的抗菌效果。本研究通过射频磁控溅射在 Ti6Al4V 表面制备了 Ag 涂层,然后研究了将改性后的合金表面在模拟体液(SBF)溶液中浸泡一个月前后的特性和抗变异性链球菌的性能。数据显示,这两种涂层在培养至七天时都能抑制变异杆菌菌落形成单位(CFU)的发展。这项研究为进一步开发牙科种植体用 Ti6Al4V 合金的表面改性提供了研究基础,以满足减少由细菌引起的种植体周围疾病的需求。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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