A randomized controlled clinical study to evaluate the efficacy of Haridra Arka in the management of Dushta Vrana vis-à-vis Chronic Non-Healing Ulcer

Ashna Ratheesh A.P., Gururaja D.
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Abstract

Introduction: A chronic wound is a wound that does not heal in an orderly set of stages and in a predictable amount of time. Any wound after 7 days is to be considered as Dushta Vrana. The use of Arka preparations in Vrana is mentioned in classics. Objective: To evaluate the efficacy of Haridra Arka in the management of Dushta Vrana and to study the anti-microbial property of Haridra Arka. Methodology: A single blind clinical study with pre-test and post-test design. The 30 patients with diagnostic criteria of Dushta Vrana were selected from Muniyal Institute of Ayurveda Medical Sciences, Manipal. In Group A, the wound is cleaned and dressed with Haridra Arka. In the control group, Betadine was used for dressing. Wound management done once in a day. Duration of the study for 30 days or till the formation of granulation tissue. Follow-up done once in 7 days for 1 month. The data were graded based on the assessment criteria and were analysed statistically. Results: The outcome of the treatment after 30 days showed high statistical significance in parameters like depth, edge and exudates amount, and other parameters like pain, itching, smell, undermining, necrotic tissue type, necrotic tissue amount, exudates type, skin colour surrounding the wound and granulation tissue showed statistical significance. Conclusion: Both these treatments showed reduction in symptoms but Group B in which Betadine was used showed better results. It can be concluded that Haridra in the form of Arka is not very effective in the management of Dushta Vrana when compared to Betadine.
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一项随机对照临床研究,评估哈里德拉-阿尔卡治疗杜什塔-弗拉纳与慢性不愈合溃疡的疗效
引言慢性伤口是指无法在可预测的时间内按部就班愈合的伤口。7 天后的伤口应视为 Dushta Vrana。经典中提到在 Vrana 中使用 Arka 制剂。目的评估 Haridra Arka 在治疗 Dushta Vrana 中的功效,并研究 Haridra Arka 的抗微生物特性。研究方法:单盲临床研究,采用前测和后测设计。从 Manipal 的 Muniyal 阿育吠陀医学科学研究所挑选了 30 名符合 Dushta Vrana 诊断标准的患者。A 组使用 Haridra Arka 清洗和包扎伤口。对照组则使用倍他丁进行包扎。每天进行一次伤口处理。研究持续 30 天或直到肉芽组织形成。每 7 天进行一次随访,为期 1 个月。根据评估标准对数据进行分级,并进行统计分析。结果30 天后的治疗结果显示,深度、边缘和渗出物量等参数具有高度统计学意义,而疼痛、瘙痒、气味、破坏、坏死组织类型、坏死组织量、渗出物类型、伤口周围皮肤颜色和肉芽组织等其他参数具有统计学意义。结论两种治疗方法都能减轻症状,但使用倍他丁的 B 组效果更好。由此可以得出结论,与贝塔丁相比,Arka 形式的 Haridra 在治疗 Dushta Vrana 方面效果不佳。
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