Evaluation of the effectiveness of various surgical techniques for early stabilization of the rib cage in comparison with conservative treatment tactics and predictors of an unfavorable outcome in patients with severe combined trauma

N. Shen, N. S. Davydova, T. V. Smelaya, E. A. Besedina, L. A. Skorokhodova, P. Boltaev, S. Y. Lukin, I. D. Panov
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Abstract

The objective was to evaluate the clinical effectiveness of various surgical techniques for early stabilization of the rib cage in comparison with conservative treatment tactics. The authors attached great importance to the search for predictors of an unfavorable outcome in patients with severe combined trauma.Materials and methods. This multicenter, non-randomized, open, retro- and prospective cohort study included 65 patients with chest trauma. Pa tients were categorized into three groups depending on the technique of restoration of the disturbed thoracic skeleton. Group 1 included 19 patients with the age of 39.9 ± 2.4 years and severity of MODS-II scale 4.0 ± 0.6, ISS 24.1 ± 1.8 points. In this group, submersible constructs were used to restore sternal reconstruction. Group 2 included 24 patients aged 30.9 ± 2.4 years with MODS-II severity score of 4.3 ± 0.5, ISS 27.1 ± 1.0 points. The stabilization of the frame was carried out using the technique of fixation of the bones of the ribs and sternum with an external fixation device (AVF). Frame stabilization was performed according to the technique of fixation of rib and sternum bones with external fixation apparatus (EFA). Group 3 contained 22 patients aged 48.6 ± 2.9 years with severity of MODS-II scale 3.9 ± 0.3, ISS 24.3 ± 1.3 points and conservative treatment tactics.Results. The respiratory biomechanics parameters in groups 1 and 2 had no statistically significant differences after 24 hours of the surgical interven tion and stabilized the rib cage. The exception concerned increased CO2 accumulation and a distinct tendency to decrease lung tissue extensibility (Slang) in the group 1, which could indicate restriction of chest excursion. The analysis of correlation between clinical and laboratory parameters and lethal outcome indicated that unfavorable outcome was most closely related to prolonged prehospital time, initial severity of the condition according to SOFA and APACHE II integral scales, as well as to the development of acute kidney injury and uncompensated tissue hypoxia.Conclusion. The comparison of the three treatment methods showed that each of them has its own advantages: the technique of surgical treatment using submersible structures is characterized by the greatest aggressiveness for the victim, limits the excursion of the chest in accordance with the biomechanics of respiration, which contributes to the aggravation of tissue hypoxia, but reduces the duration of treatment and financial costs. The least expensive, but comparable in aggressiveness, is the method of hardware fixation. The most sparing for the patient, although lengthening the time of treatment and, accordingly, its cost, is the conservative method of management. Thus, the choice of surgical tactics is left to the attending physician and the patient.
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与保守治疗方法相比,评估早期稳定肋骨骨架的各种外科技术的有效性,以及严重合并创伤患者不利结局的预测因素
目的是评估早期稳定肋骨笼的各种外科技术与保守治疗策略的临床效果。作者非常重视寻找严重合并创伤患者不良预后的预测因素。这项多中心、非随机、开放、追溯和前瞻性队列研究包括 65 名胸部创伤患者。根据受干扰胸廓骨骼的修复技术,患者被分为三组。第一组包括 19 名患者,年龄为(39.9±2.4)岁,MODS-II 评分为(4.0±0.6)分,ISS 为(24.1±1.8)分。该组患者使用潜水构造恢复胸骨重建。第二组包括 24 名患者,年龄为(30.9±2.4)岁,MODS-II 严重程度评分为(4.3±0.5)分,ISS 为(27.1±1.0)分。采用外固定装置(AVF)固定肋骨和胸骨的技术进行框架稳定。第 2 组有 22 名患者,年龄为 48.0 岁(±1.0 分);第 3 组有 22 名患者,年龄为 48.0 岁(±1.0 分)。第 3 组包括 22 名患者,年龄为(48.6±2.9)岁,MODS-II 评分为(3.9±0.3)分,ISS 为(24.3±1.3)分,采取保守治疗策略。手术干预 24 小时后,第 1 组和第 2 组的呼吸生物力学参数在统计学上无显著差异,肋骨保持稳定。但第 1 组二氧化碳蓄积增加,肺组织伸展性(Slang)明显下降,这可能表明胸廓外展受限。临床和实验室参数与死亡结果之间的相关性分析表明,不利的结果与院前时间过长、SOFA 和 APACHE II 积分表显示的最初病情严重程度以及急性肾损伤和未补偿的组织缺氧的发展关系最为密切。对三种治疗方法的比较表明,它们各有各的优势:使用潜水结构的外科治疗技术的特点是对受害者的攻击性最强,根据呼吸的生物力学限制了胸腔的扩张,从而导致组织缺氧加重,但缩短了治疗时间,降低了经济成本。硬件固定法费用最低,但具有可比性。对病人来说,最省钱的方法是保守治疗法,虽然会延长治疗时间,相应地也会增加治疗费用。因此,手术方法的选择权在主治医生和患者手中。
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