Clinical case of an atypical course of autoimmune anti-NMDA encephalitis

V. V. Goldobin, E. Klocheva, A. Dil, V. I. Golovkin, I. V. Chistova
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Abstract

Autoimmune encephalitis with antibodies against NMDA receptor (anti-NMDA encephalitis) is a relatively newly described disease that occupies a leading position among encephalitis of various etiologies. The article presents diagnostic criteria for this disease and describes a case of an atypical course of confirmed anti-NMDA encephalitis. The peculiarities of this observation are the relatively mild course of the disease with the development of generalized seizures, mental and cognitive disorders at the onset of the disease. The difficulties in diagnosis and possible pathogenetic aspects of the disease are discussed.
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自身免疫性抗 NMDA 脑炎非典型病程的临床病例
具有 NMDA 受体抗体的自身免疫性脑炎(抗 NMDA 脑炎)是一种较新描述的疾病,在各种病因引起的脑炎中占主导地位。文章介绍了这种疾病的诊断标准,并描述了一例确诊的抗 NMDA 脑炎的非典型病程。该病例的特点是病程相对较轻,发病时出现全身抽搐、精神和认知障碍。本文讨论了该病的诊断困难和可能的致病因素。
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