A CLINICAL STUDY TO EVALUATE THE EFFECT OF VIRECHANA WITH TRIPHALADI CHOORNA IN THE MANAGEMENT OF PSORIASIS

Shalini Katoch, Rajalaxmi M G, Niranjan Rao
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Abstract

Virechana is among the Pancha Shodhana and Panchakarma, as explained by Acharyas in the classics. Virechana is the procedure in which the orally administered Dravyas act on internally vitiated Doshas, specifically Pitta, and expels them through Gudamarga. Psoriasis is a chronic, recurrent, inflammatory disease of the skin of unknown origin, characterised by well-circumscribed erythematous, dry plaques of various sizes covered with scales. The Prevalence of Psoriasis varies across countries, ranging from 0.09-11.43%. Globally, it is estimated that at least 100 million individuals are affected by Psoriasis. In India, the reported incidence varies from 0.44- 2.8% among skin disorders, with an overall incidence of 1.02%. In Ayurveda, various skin diseases are classified under the broad category of Kushta. Features of Psoriasis resemble multiple types of Kushta. Hence, this clinical study of Virechana with Triphaladi Choorna was taken to assess its efficacy in this disease. The assessment used parameters like PASI Score, Auspitz sign, and Candle grease sign. Objectives: To evaluate the effect of Virechana with Triphaladi Choorna in the management of Psoriasis. Methods: This is an open-label clinical study with pre-test and post-test design wherein 20 patients diagnosed with Psoriasis and fulfilling the selection criteria in the age group of 18 – 70 years of either gender were selected from the OPD/IPD. Results: The study showed a statistically significant result in decrement in PASI Score with a change from before treatment to after follow-up. Interpretation and Conclusion: Hence, Virechana Karma with Triphaladi Choorna was found to be effective in reducing signs and symptoms of Psoriasis
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一项临床研究,评估三叶草皂苷治疗银屑病的效果
Virechana 是阿查里亚在经典中解释的 Pancha Shodhana 和 Panchakarma 之一。Virechana 是口服 Dravyas 对内部受损的 Doshas(特别是 Pitta)起作用并通过 Gudamarga 将其排出的过程。牛皮癣是一种慢性、复发性、原因不明的皮肤炎症性疾病,其特征是皮肤上覆盖着大小不等的圆形红斑和干燥的鳞屑。银屑病的发病率因国家而异,从 0.09% 到 11.43% 不等。据估计,全球至少有 1 亿人患有银屑病。在印度,皮肤病的报告发病率为 0.44-2.8%,总发病率为 1.02%。在阿育吠陀中,各种皮肤病被归入 Kushta 大类。银屑病的特征与多种 Kushta 相似。因此,本临床研究采用了 Virechana 和 Triphaladi Choorna,以评估其对该疾病的疗效。评估使用了 PASI 评分、奥斯皮茨征和烛脂征等参数。目的评估 Virechana 和 Triphaladi Choorna 对银屑病的治疗效果。方法:这是一项开放标签临床试验:这是一项开放标签临床研究,采用前测和后测设计,从门诊部/综合病房选取 20 名年龄在 18 - 70 岁之间、符合选择标准的银屑病患者。研究结果研究显示,从治疗前到随访后,PASI 评分的下降具有统计学意义。解释和结论:因此,使用 Triphaladi Choorna 的 Virechana Karma 能有效减轻银屑病的症状和体征。
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