MANAGEMENT OUTCOMES AND DETERMINANTS OF PAPILLARY MICROCARCINOMA THYROID

Azim Khan, Mubashir D, Sobin Sunny
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Abstract

Background Papillary microcarcinoma thyroid (PMCT) accounts for around 85% of the thyroid malignancies. Most of the autopsy series did not reveal differences in incidence with respect to gender, age, thyroid size, or multifocality. With advances in ultrasonography and ne-needle aspiration biopsies, especially in mass screening programs, PMCT can be diagnosed before surgery. This study was conducted with the aim of understanding the determinants of PMCT. Methods A cross-sectional observational study was conducted at a surgery department. All patients diagnosed with PMCT in thyroidectomy specimen from 2003 to 2019 were studied. The case sheets and histopathology reports were retrieved from the computerised ling system. The case sheets and histopathology reports were retrieved from the computerised ling system. Results Out of the 140 cases studied there were 111 (79.0%) incidental cases and 29 (21.0%) non incidental cases of PMCT. Females were associated with higher chance of having incidental PMCT. Smaller size lesions were more associated with incidental PMCT. Conclusion Patients with the associated clinical risk factors should be observed carefully and periodically followed up. This can help in recognizing the occurrence of frank malignancy, the outcome of the disease and planning the appropriate timely management.
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甲状腺乳头状微癌的管理结果和决定因素
背景甲状腺乳头状微癌(PMCT)约占甲状腺恶性肿瘤的85%。大多数尸检系列并未发现发病率与性别、年龄、甲状腺大小或多发性有关。随着超声波检查和 ne-needle aspiration biopsies(尤其是在大规模筛查项目中)技术的进步,PMCT可以在手术前得到诊断。本研究旨在了解 PMCT 的决定因素。方法 在一个外科部门进行了一项横断面观察研究。研究对象为2003年至2019年期间在甲状腺切除术标本中被诊断为PMCT的所有患者。病例表和组织病理学报告均从计算机 ling 系统中提取。病例表和组织病理学报告从计算机化的 ling 系统中检索。结果 在所研究的140例病例中,有111例(79.0%)为偶发病例,29例(21.0%)为非偶发病例。女性偶发 PMCT 的几率更高。病变体积较小的患者更容易偶发 PMCT。结论 对具有相关临床危险因素的患者应进行仔细观察和定期随访。这有助于识别坦率的恶性肿瘤的发生、疾病的预后以及计划适当的及时治疗。
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