HISTORY OF PATIENTS WITH NEW CORONAVIRUS INFECTION AND PRETERM BIRTH

Vrach Pub Date : 2024-01-31 DOI:10.29296/25877305-2024-01-06
Е. Chernaya, Е. Kutefa
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Abstract

Purpose. To study the anamnesis of patients who have suffered a new coronavirus infection (NCI) and preterm birth (PB). Material and methods. A retrospective study of the anamnesis of patients who underwent NCI in the second half of pregnancy and PB was carried out in the period from May 2020 to December 2021. The division into groups was carried out taking into account the timing of delivery: Group 1 (n=104) – term birth at 37 weeks of gestation and later; Group 2 (n=44) – PB from 22 to 36+6 weeks of gestation. Results. The combination of diseases such as chronic bronchitis, maxillary sinusitis and bronchial asthma increased the risk of PB against the background of NCI by 3.4 times (95% confidence interval [CI] – 2.65–4.39). Among extragenital diseases, opisthorchiasis was detected 4.7 times more often in patients with PB (95% CI – 1.308–17.097). In group 2, compared with group 1, among pregnancy complications, moderate anemia was 6.5 times more likely to be observed (95% CI – 1.2–35.1). PB were due to the severe course of COVID pneumonia and its progression, the serious condition of the woman, which required the prescription of etiotropic therapy. In this regard, the probability of cesarean section in group 2 was 12.6 times higher (95% CI – 4.2–37.8) compared to group 1.
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新冠状病毒感染和早产患者的病史
目的研究新冠状病毒感染(NCI)和早产(PB)患者的病史。在 2020 年 5 月至 2021 年 12 月期间,对妊娠后半期感染新冠状病毒和早产的患者的病史进行了回顾性研究。根据分娩时间进行分组:第1组(n=104)--妊娠37周及以后的足月产;第2组(n=44)--妊娠22周至36+6周的PB。结果显示,慢性支气管炎、上颌窦炎和支气管哮喘等疾病的合并症会使在妊娠期感染NCI的孕妇发生早产的风险增加3.4倍(95%置信区间[CI] - 2.65-4.39)。在生殖器外疾病中,乳头瘤病毒感染在 PB 患者中的检出率是其他疾病的 4.7 倍(95% 置信区间 - 1.308-17.097)。与第一组相比,第二组妊娠并发症中中度贫血的发生率是第一组的 6.5 倍(95% CI - 1.2-35.1)。PB 是由于 COVID 肺炎的严重病程及其进展,以及产妇的严重状况,需要处方抗生素治疗。在这方面,与第一组相比,第二组的剖宫产概率高出 12.6 倍(95% CI - 4.2-37.8)。
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