Sulodexide in clinical practice: possibilities and prospects of its use

Abstract

Objective: to analyze up-to-date information about the efficiency of using sulodexide n clinical practice. Current publication on the efficacy and safety of sulodexide, as well as information on the pathogenesis and clinical manifestations of chronic venous insufficiency, microvascular angina, venous thromboembolic events, and diabetes mellitus have been sought for and analyzed Most clinical trials show that sulodexide exerts anti-inflammatory, endothelium-protective, and pleotrophic effects, by confirming its potential efficacy in the treatment of cardiovascular diseases, in particular chronic vein diseases, microvascular anginas, and venous thromboembolic events. Sulodexide as an additional therapy is used to treat type 2 diabetes mellitus.