Analytical and antimicrobial study of herbo-mineral formulation Shwasakasari Rasa in selected respiratory micro-organism

Neelam Malviya, Anil Nagle, R.K. Pati
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Abstract

Shwasakasari Rasa (SKR) is mentioned in Rasa Yoga Sagar,[1] (part 2) as a remedy of Shwasa & Kaasa Roga. This type of Rasa Aushadhi are more effective against bacteria. These drugs have a multi dimension effect like Broad-spectrum antibiotics. The Rasaushadies mentioned in Ayurvedic Pharmacopoeia should be analysed for physical & chemical properties to confirm purity & safety before administration in human beings. Hence it become obligatory to adopt modern analytical methodology for better understanding and interpretation of physio-chemical changes occurred during the process. SKR was analysed on the following parameter Organoleptic parameter, Physiochemical analysis, Advanced physiochemical analysis. SKR sample was tested for antimicrobial activity against standard strains of Staphylococcus aureus, Klebsiella pneumonia and Streptococcus pneumonia. The prepared Shwasakasari Rasa was studied for their MIC (Minimum Inhibitory Concentration & the zone of inhibition. The prepared drug was compared with Azithromycin (standard drug) of macrolide group to evaluate its antimicrobial efficacy. These tests was conducted in, S.R Labs & Research Centre, Jaipur.
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草本矿物质配方 Shwasakasari Rasa 对特定呼吸道微生物的分析和抗菌研究
Shwasakasari Rasa(SKR)在《Rasa Yoga Sagar》[1](第 2 部分)中作为 Shwasa 和 Kaasa Roga 的一种疗法被提及。这类 Rasa Aushadhi 对细菌更有效。这些药物与广谱抗生素一样具有多维效果。阿育吠陀药典》中提到的 Rasaushadies 在对人体用药前应进行物理和化学特性分析,以确认其纯度和安全性。因此,有必要采用现代分析方法,以便更好地理解和解释加工过程中发生的物理化学变化。对 SKR 进行了以下分析:感官参数、理化分析、高级理化分析。测试了 SKR 样品对金黄色葡萄球菌、肺炎克雷伯氏菌和肺炎链球菌标准菌株的抗菌活性。研究了所制备的 Shwasakasari Rasa 的 MIC(最低抑菌浓度)和抑菌区。制备的药物与大环内酯类的阿奇霉素(标准药物)进行了比较,以评估其抗菌功效。这些测试在斋浦尔的 S.R 实验室和研究中心进行。
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