Etiological Factors Contributing to Orbital and Oculoplastic Conditions at University Teaching Hospital in Zambia: A Comprehensive Analysis

Juliet Mulenga, Brian Ng’andwe, Phyliss Moonga, John Buchan, Allen Foster
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Abstract

Purpose: Orbital, Oculoplastic including Ocular Oncology are not only sight threatening but potentially life threatening. This study examines the causes of these conditions at University Teaching Hospitals-Eye Hospital in Lusaka Zambia. Methods: A retrospective review of 150 case files of patients with an Orbital, Oculoplastic and Ocular Oncology diagnosis presenting at UTHs-EH over a 4-year period, 2018-2021. Results: Of the 150 cases 54% were under the age of 40 years.  The most common condition seen was squamous cell carcinoma of the conjunctiva (SCC), usually confined to the globe, but sometimes spreading to the orbit. There was a positive association between HIV infection and SCC. Conclusion: This study at University Teaching Hospital revealed a spectrum of orbital and oculoplastic diseases, with Squamous Cell Carcinoma emerging as a predominant concern. The insights gained pave the way for enhanced service delivery.  These findings, while specific to Zambia, hold relevance for the broader African context, offering a basis for future assessments, interventions, and policy enhancements.
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赞比亚大学教学医院眼眶和眼部整形疾病的病因:综合分析
目的:眼眶、眼部整形包括眼部肿瘤不仅威胁视力,还有可能危及生命。本研究对赞比亚卢萨卡大学教学医院眼科医院的这些病症的病因进行了调查。研究方法回顾性审查2018-2021年4年间在UTHs-EH就诊的150例眼眶、眼部整形和眼部肿瘤诊断患者的病历。结果:在150个病例中,54%的患者年龄在40岁以下。 最常见的病症是结膜鳞状细胞癌(SCC),通常局限于球部,但有时会扩散至眼眶。艾滋病病毒感染与鳞状细胞癌呈正相关。结论这项在大学教学医院进行的研究揭示了眼眶和眼部整形疾病的范围,其中鳞状细胞癌成为主要的关注点。所获得的启示为更好地提供服务铺平了道路。 这些研究结果虽然只针对赞比亚,但在更广泛的非洲背景下具有现实意义,为今后的评估、干预和政策改进提供了依据。
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