Walter R Duarte-Celada, Samathorn Thakolwiboon, Jie Pan, Tulio Bueso, Jannatul Ferdous
{"title":"Cefepime-induced non-convulsive status epilepticus","authors":"Walter R Duarte-Celada, Samathorn Thakolwiboon, Jie Pan, Tulio Bueso, Jannatul Ferdous","doi":"10.12746/swrccc.v12i50.1277","DOIUrl":null,"url":null,"abstract":"Cefepime-induced non-convulsive status epilepticus (NCSE) can develop in patients with advanced age, renal impairment, and previous central nervous system disorders. Its clinical presentation varies from confusion, mutism, and decreased level of consciousness to coma. The typical electroencephalogram (EEG) findings are generalized spike and wave discharges of 1-3 Hz. We present a case series of 4 patients with cefepime-induced NCSE, including the clinical presentation and EEG findings. Electroencephalograms should be part of the workup of acute confusional state in patients on this antibiotic, and physicians should be aware of this uncommon complication. \n \nKeywords: Non-convulsive status epilepticus, cefepime, confusion, mutism, electroencephalogram.","PeriodicalId":22976,"journal":{"name":"The Southwest Respiratory and Critical Care Chronicles","volume":"183 1-2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Southwest Respiratory and Critical Care Chronicles","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12746/swrccc.v12i50.1277","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Cefepime-induced non-convulsive status epilepticus (NCSE) can develop in patients with advanced age, renal impairment, and previous central nervous system disorders. Its clinical presentation varies from confusion, mutism, and decreased level of consciousness to coma. The typical electroencephalogram (EEG) findings are generalized spike and wave discharges of 1-3 Hz. We present a case series of 4 patients with cefepime-induced NCSE, including the clinical presentation and EEG findings. Electroencephalograms should be part of the workup of acute confusional state in patients on this antibiotic, and physicians should be aware of this uncommon complication.
Keywords: Non-convulsive status epilepticus, cefepime, confusion, mutism, electroencephalogram.