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Lentil aspiration pneumonitis 扁豆吸入性肺炎
Pub Date : 2024-07-16 DOI: 10.12746/swrccc.v12i52.1181
Tasmea Haque, Pragati Basera, Tushi Singh, Dauod Arif
This patient has a complex medical history that includes intellectual disability, blindness, deafness, seizure disorder, tracheomalacia, and recurrent aspiration. He had a percutaneous endoscopic gastrostomy in place for tube feeding. He again presented with acute respiratory distress, hypoxemia, fever, and leukocytosis. Chest computed tomography (CT) revealed bilateral infiltrates and nodular densities. A previous chest CT done 6 years prior to admission revealed multiple micronodules scattered throughout both lung fields. The patient had had a previous lung biopsy 20 years prior to admission which revealed lentil starch material in bronchioles and multifocal foreign body giant cell reactions. The patient was treated with an empiric antibiotic regimen and improved. This case demonstrates the radiographic and histologic changes associated with lentil pneumonia which is an unusual type of aspiration pneumonia. Keywords: Lentil pneumonia, granulomas, aspiration, nodules
该患者病史复杂,包括智力残疾、失明、失聪、癫痫发作、气管麻痹和反复吸入。他接受了经皮内镜胃造瘘术,以便进行管饲。他再次出现急性呼吸窘迫、低氧血症、发烧和白细胞增多。胸部计算机断层扫描(CT)显示双侧浸润和结节状密度。入院前6年做的胸部CT显示,双侧肺野散布着多个微小结节。患者在入院前20年曾做过一次肺活检,结果显示支气管内有扁豆淀粉物质和多灶异物巨细胞反应。患者接受了经验性抗生素治疗,病情有所好转。本病例显示了扁桃体肺炎的影像学和组织学变化,这是一种不常见的吸入性肺炎。关键词:扁桃体肺炎、肉芽肿扁桃体肺炎 肉芽肿 吸入性 结节
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引用次数: 0
Severe outcome in rare upper extremity phlegmasia cerulea dolens 罕见的上肢痰多症的严重后果
Pub Date : 2024-07-16 DOI: 10.12746/swrccc.v12i52.1337
Jose Ramos, Colby Wood
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引用次数: 0
Pneumocystis jirovecii pneumonia secondary to chronic steroid use: An uncommon cause of pneumocystis pneumonia 因长期使用类固醇而继发的肺孢子菌肺炎:引起肺孢子虫肺炎的一个不常见原因
Pub Date : 2024-07-16 DOI: 10.12746/swrccc.v12i52.1321
Mandvi Pandey, Nithila Sivakumar, Anunaya Aashish, Dhruvangkumar Modi
Patients on long-term immunosuppression, including corticosteroids or immunomodulatory drugs, are susceptible to opportunistic infections, such as like Pneumocystis jirovecii pneumonia (PJP). Corticosteroid use can increase the frequency of fungal infection, mask symptoms, and delay the diagnosis, and thus warrant preventive measures. Maintaining a high index of suspicion is important, and prophylactic antibiotics, particularly trimethoprim-sulfamethoxazole, should be considered for high-risk patients. This case underscores the diagnosis of PJP in a patient with interstitial lung disease receiving prolonged steroid therapy, despite lacking HIV and conventional risk factors for this infection. Notably, PJP can present as a more severe infection in non-HIV patients, leading to higher mortality rates and stressing the need for swift and effective diagnosis and treatment by healthcare providers. Keywords: Pneumocystis jirovecii; pneumonia; chronic corticosteroid treatment use; fungal pneumonia; interstitial lung disease
长期使用皮质类固醇或免疫调节药物等免疫抑制剂的患者很容易发生机会性感染,如肺孢子菌肺炎(PJP)。使用皮质类固醇会增加真菌感染的频率,掩盖症状,延误诊断,因此需要采取预防措施。保持高度怀疑非常重要,高危患者应考虑使用预防性抗生素,尤其是三甲双胍-磺胺甲噁唑。本病例强调了对长期接受类固醇治疗的间质性肺病患者的 PJP 诊断,尽管该患者缺乏 HIV 感染和常规感染风险因素。值得注意的是,PJP 在非 HIV 患者中可能表现为更严重的感染,从而导致更高的死亡率,这也强调了医护人员迅速有效诊断和治疗的必要性。关键词肺孢子菌;肺炎;长期使用皮质类固醇治疗;真菌性肺炎;间质性肺病
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引用次数: 0
Diabetic ketoacidosis resolution: From the traditional way to guideline-based management in the MICU at University Medical Center, Lubbock, Texas 解决糖尿病酮症酸中毒问题:德克萨斯州卢伯克大学医疗中心 MICU 从传统方法到基于指南的管理方法
Pub Date : 2024-07-16 DOI: 10.12746/swrccc.v12i52.1327
A. Motes, Tushi Singh, Myrian N VINAN VEGA, Divya Vangipuram-Wyatt, Joscilin Mathew, Kenneth Nugent
Diabetes is a chronic, metabolic disease characterized by hyperglycemia which eventually can cause serious organ damage. The prevalence of diabetes has steadily increased over the past few decades, and approximately 1.4 million Americans are diagnosed with diabetes every year. Diabetes was the seventh leading cause of death in the United States in 2019. Diabetic ketoacidosis (DKA) is a serious complication of diabetes that can be life-threatening. It occurs more frequently in the patients with type 1 diabetes but can also develop in people with type 2 diabetes. It was determined that the average cost per DKA episode was $6,444, and that the annual cost of medical treatment in a diabetic patient with a prior episode of DKA was 2.67 times higher than a diabetic patient with no history of DKA. The criteria for DKA resolution at University Medical Center (UMC) in Lubbock, Texas, are different from current American Diabetes Association (ADA) guidelines. At UMC, a plasma bicarbonate ≥18 mEq/L, a venous pH > 7.3, and anion gap ≤12 mEq/L must be recorded twice (4 hours apart) before bridging to subcutaneous long-acting insulin administration. This time requirement could contribute to a longer time for DKA resolution and longer intensive care unit and hospital stays.Keywords: Diabetic ketoacidosis, DKA resolution
糖尿病是一种以高血糖为特征的慢性代谢性疾病,最终会造成严重的器官损伤。在过去几十年里,糖尿病的发病率稳步上升,每年约有 140 万美国人被诊断出患有糖尿病。2019 年,糖尿病是美国第七大死因。糖尿病酮症酸中毒(DKA)是糖尿病的一种严重并发症,可危及生命。它多发于 1 型糖尿病患者,但也可能发生在 2 型糖尿病患者身上。研究发现,每次 DKA 病发的平均费用为 6,444 美元,曾有过 DKA 病发经历的糖尿病患者每年的医疗费用是没有 DKA 病史的糖尿病患者的 2.67 倍。德克萨斯州卢伯克大学医学中心(UMC)的 DKA 诊断标准与美国糖尿病协会(ADA)的现行指南不同。在 UMC,血浆碳酸氢盐≥18 mEq/L、静脉 pH > 7.3 和阴离子间隙≤12 mEq/L 必须记录两次(间隔 4 小时),然后才能转为皮下注射长效胰岛素。这一时间要求可能导致 DKA 缓解时间延长,重症监护室和住院时间延长:糖尿病酮症酸中毒 DKA 缓解
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引用次数: 0
Cardiopulmonary exercise testing in post-COVID-19 patients COVID-19后患者的心肺运动测试
Pub Date : 2024-07-16 DOI: 10.12746/swrccc.v12i52.1329
Kenneth Nugent
Abstract Patients with prior COVID-19 infection can have residual symptoms and significant disability.  In particular, some patients have abnormal lung function with reduced volumes and diffusion capacities.  However, some patients have relatively normal lung function and chest x-rays but have significant dyspnea.  These patients have been evaluated using cardiopulmonary exercise testing (CPET) to determine their peak O2 consumption and their cardiac and respiratory responses during standardized testing.  In general, these studies demonstrate that the level of impairment correlates with the severity of the initial infection.  In addition, some patients have little or no improvement in their VO2 over time.  This test can provide some insight as to exact system limitations resulting in impairment. Six-minute walk tests provide alternative approaches for evaluating patients when CPET testing is not available.  Most patients who have had prior COVID infection improve with standard pulmonary rehabilitation. Keywords: COVID-19 infection, dyspnea, cardiopulmonary exercise testing, rehabilitation
摘要 曾感染 COVID-19 的患者可能会有后遗症和严重残疾。 特别是,有些患者的肺功能异常,肺容积和弥散能力下降。 然而,有些患者的肺功能和胸部 X 光片相对正常,但却有明显的呼吸困难。 这些患者通过心肺运动测试(CPET)进行评估,以确定他们在标准化测试中的氧气消耗峰值及其心脏和呼吸反应。 一般来说,这些研究表明,损伤程度与最初感染的严重程度相关。 此外,随着时间的推移,有些患者的氧气消耗量几乎没有改善。 这项测试可以帮助我们了解导致功能受损的确切系统限制。在无法进行 CPET 测试时,六分钟步行测试可作为评估患者的替代方法。 大多数曾感染过 COVID 的患者都能通过标准的肺康复治疗得到改善。关键词COVID-19 感染 呼吸困难 心肺运动测试 康复
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引用次数: 0
Nafcillin-induced thrombocytopenia: An uncommon complication 萘夫西林诱发的血小板减少症:一种不常见的并发症
Pub Date : 2024-07-16 DOI: 10.12746/swrccc.v12i52.1305
Zain Amar, Muneeb Rehman, Alfredo Iardino, Yasir Ahmed
Drug-induced thrombocytopenia is a challenging clinical dilemma that is often overlooked. Nafcillin is a beta-lactam anti-staphylococcal penicillin antibiotic used as a first-line treatment for methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia and severe infections. Nafcillin has been associated with a higher rate of premature antibiotic discontinuation than cefazolin. Here we report a 58-year-old woman with multiple comorbid conditions who presented with a prosthetic right hip joint infection due to MSSA and was treated with nafcillin but developed profound thrombocytopenia due to a possible nafcillin side effect on the 14th day of therapy. Thrombocytopenia resolved after discontinuation of nafcillin, and the patient was treated successfully with cefazolin. Keywords: Nafcillin-induced thrombocytopenia, drug-induced thrombocytopenia, thrombocytopenia
药物诱发的血小板减少症是一个极具挑战性的临床难题,常常被忽视。萘夫西林是一种β-内酰胺类抗葡萄球菌青霉素抗生素,用于甲氧西林易感金黄色葡萄球菌(MSSA)菌血症和严重感染的一线治疗。与头孢唑啉相比,萘夫西林的过早停药率更高。在此,我们报告了一名患有多种并发症的 58 岁女性患者,她因 MSSA 引起右髋关节假体感染,接受了萘夫西林治疗,但在治疗的第 14 天,由于可能存在的萘夫西林副作用,她出现了严重的血小板减少症。停用萘夫西林后,血小板减少症状缓解,患者成功接受了头孢唑啉治疗。关键词:萘西林萘夫西林诱导的血小板减少症 药物诱导的血小板减少症 血小板减少症
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引用次数: 0
Uncharted Territory Navigating a Rare Candida Albicans Liver Abscess Case 探索罕见念珠菌肝脓肿病例的未知领域
Pub Date : 2024-07-16 DOI: 10.12746/swrccc.v12i52.1323
Letisha Mirembe, Abhijit Gutal
This case report describes a rare instance of Candida albicans liver abscess in a 46-year-old immunocompetent male with extensive medical history. The report underscores the diagnostic challenges in such atypical presentations and emphasizes the critical role of a multidisciplinary approach for effective management, highlighting the unusual nature of the case in the context of the patient's immune competence.  
本病例报告描述了一例罕见的白色念珠菌肝脓肿病例,患者是一名 46 岁的免疫功能正常男性,病史丰富。报告强调了此类非典型病例的诊断难题,并强调了多学科方法在有效管理中的关键作用,同时强调了该病例在患者免疫能力方面的不寻常性。
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引用次数: 0
Management of post-extubation anxiety in the intensive care unit 重症监护病房拔管后焦虑症的管理
Pub Date : 2024-07-16 DOI: 10.12746/swrccc.v12i52.1269
Vaibhav Oberoi, A. Sekhon, Ashish Sarangi
Post-extubation anxiety causes significant distress in intensive care unit patients. This review provides treatment recommendations for managing anxiety during weaning and extubation from mechanical ventilation. Factors predisposing to anxiety include cerebral vascular disease, endocrine disorders, cardiopulmonary decompensation, disrupted sleep-wake cycles, and the stressful ICU environment. This review analyzed 21 articles sourced from Google Scholar and PubMed, focusing on case reports, case series, systematic reviews, and meta-analyses. These studies reported that dexmedetomidine effectively reduces extubation time and ICU length of stay through its anxiolytic properties. Antipsychotics, like quetiapine, showed potential in managing anxiety during ventilator weaning, but high-dose haloperidol posed risks. Benzodiazepines were linked to paradoxical agitation and respiratory suppression. Non-pharmacological treatments, such as aromatherapy, music therapy, and massage therapy, appeared to reduce anxiety and improve sleep quality. Caregiver approaches, including parental presence and psychological training, also reduced anxiety. In conclusion, non-pharmacological approaches should be prioritized, and pharmacological treatments considered when necessary. More research is essential to identify optimal treatments for post-extubation anxiety with minimal patient risk and effective symptom control. Keywords: Anxiety, ICU patients, critically ill patients, post-extubation
拔管后焦虑会给重症监护病房的患者带来极大的痛苦。本综述提供了在机械通气断奶和拔管期间控制焦虑的治疗建议。导致焦虑的因素包括脑血管疾病、内分泌失调、心肺功能减退、睡眠-觉醒周期紊乱以及紧张的重症监护室环境。本综述分析了谷歌学术和 PubMed 上的 21 篇文章,重点关注病例报告、系列病例、系统综述和荟萃分析。这些研究报告指出,右美托咪定具有抗焦虑特性,可有效缩短拔管时间和重症监护室的住院时间。抗精神病药物(如喹硫平)在控制呼吸机断奶期间的焦虑方面具有潜力,但大剂量氟哌啶醇会带来风险。苯二氮卓类药物与矛盾性躁动和呼吸抑制有关。芳香疗法、音乐疗法和按摩疗法等非药物疗法似乎可以减轻焦虑并改善睡眠质量。照顾者的方法,包括父母陪伴和心理训练,也能减轻焦虑。总之,应优先考虑非药物疗法,必要时再考虑药物疗法。更多的研究对于确定治疗拔管后焦虑症的最佳方法至关重要,这样既能将患者的风险降至最低,又能有效控制症状。关键词焦虑 ICU 重症患者 插管后
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引用次数: 0
Update-Exposure to dust events and hospitalizations in West Texas cities: The human health consequences of dust 更新-德克萨斯州西部城市的沙尘事件暴露和住院情况:沙尘对人类健康的影响
Pub Date : 2024-07-16 DOI: 10.12746/swrccc.v12i52.1325
Thomas E. Gill, Estrella Herrera-Molina, G. Ibarra-Mejía, Soyoung Jeon, Karin Ardon-Dryer
in dust-associated diseases, more consistent monitoring of dust levels should be implemented across the western USA, not just in the major cities where detailed measurements are now available. Our research team is currently investigating the health effects of dust in other West Texas cities, including Amarillo and Midland, and evaluating the potential health effects of thunderstorms, which have been shown to impact other cities in the USA and across the globe. We are also determining the incidence of coccidioido-mycosis (Valley fever), caused by the soil-dwelling fungus Coccidioides and potentially associated with dust and wind in West Texas. We actively welcome collaborations with other researchers and students.
为了减少与粉尘有关的疾病的发病率,应该在美国西部对粉尘水平进行更加一致的监测,而不仅仅是在目前已经有详细测量数据的大城市。我们的研究团队目前正在调查德克萨斯州西部其他城市(包括阿马里洛和米德兰)的沙尘对健康的影响,并评估雷暴对健康的潜在影响,雷暴已被证明会影响美国和全球的其他城市。我们还在确定球孢子菌病(山谷热)的发病率,该病由生活在土壤中的球孢子菌引起,可能与西得克萨斯州的灰尘和风有关。我们积极欢迎与其他研究人员和学生合作。
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引用次数: 0
Subacute inferior vena cava occlusion after treatment for advanced colorectal cancer: presentation and management 晚期结直肠癌治疗后亚急性下腔静脉闭塞:表现与处理
Pub Date : 2024-07-16 DOI: 10.12746/swrccc.v12i52.1287
Letisha Mirembe, Devin Bird, Robyn Tapp, Bailey Gutierrez, Haven Ward, I. Obokhare
Thrombosis of the inferior vena cava is an uncommon condition and may not be recognized until the affected patient develops severe symptoms. It is associated with a higher risk of complications than other locations of deep venous thrombosis. Here we present a case of a 72-year-old man with bilateral occlusion of the external iliac veins and inferior vena cava. Keywords: Inferior vena cava, thrombosis, managemen
下腔静脉血栓是一种不常见的疾病,可能直到患者出现严重症状时才被发现。与其他部位的深静脉血栓形成相比,下腔静脉血栓形成的并发症风险更高。在此,我们介绍一例双侧髂外静脉和下腔静脉闭塞的 72 岁男性患者。关键词:下腔静脉下腔静脉、血栓形成、处理
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引用次数: 0
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The Southwest Respiratory and Critical Care Chronicles
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