The Correlation Between GRACE Risk Score and SYNTAX Angiographic Score in Acute Coronary Syndrome: A Cross-Sectional Study

Abstract

Background: The Global Registry of Acute Coronary Events (GRACE) is used in patients with acute coronary syndrome (ACS) to stratify the risk of mortality. The Synergy Between Percutaneous Coronary Intervention (SYNTAX) score explains the extent of coronary artery disease (CAD) and guides to an appropriate treatment strategy. Objectives: This study aimed to determine the correlation between GRACE and SYNTAX scores. Methods: A total of 101 ACS patients were recruited in this case-control study. Coronary angiography (CA) was performed for all of the participants. Correlation analysis was performed to investigate the relationship between GRACE risk and SYNTAX angiographic scores. Results: A total of 83 men and 18 women who had ACS with an average age of 57.2 ± 11.6 years (minimum of 33 and maximum of 89 years) were investigated. The SYNTAX angiographic score and the GRACE risk score for participants of this study were 15.09 ± 5.87 and 114.47 ± 26.2, respectively. A strong positive correlation, which was statistically significant, was demonstrated between the GRACE risk score and the SYNTAX angiographic score (r = 0.867, P < 0.001) Conclusions: Our findings point out a significant strong positive correlation exists between GRACE risk score and SYNTAX angiographic score in patients with unstable angina (UA), ST-elevation myocardial infarction (STEMI), or non-ST elevation myocardial infarction (NSTEMI).