Stepwise implementation of an enhanced recovery pathway for elective total hip arthroplasty in a Swiss hospital: a cohort study

Simon Heinrich, Simon Gratza, A. Eckardt, Thomas Ilchmann
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Abstract

BACKGROUND: Enhanced recovery programs after total hip arthroplasty have been shown to reduce hospital length of stay without compromising results, but yet there is a lack of data for the Swiss population. Therefore, this retrospective cohort study evaluated whether similar positive effects on clinical outcomes are present in the context of the Swiss healthcare system. METHODS: Patients who underwent elective primary total hip arthroplasty were analysed. The baseline group comprised 50 patients treated consecutively by one surgeon in 2013 according to the clinical practice guidelines. Another surgeon implemented a new standardised treatment protocol in April 2014. In January 2018, this protocol was followed by an enhanced recovery program that integrated all care providers at the hospital. The data of the baseline group (series 0) and four series of 50 patients each, two treated with the standardised treatment protocol (series 1–2) and two treated with the enhanced recovery program (series 3–4), were analysed. All patients had follow-ups at 6 weeks and 3 months after surgery. The primary outcomes were length of stay and discharge destination; the secondary outcomes were admission on the day of surgery (instead of one day prior), the use of urinary catheters, the administration of opioids, the difference between pre- and postoperative haemoglobin, blood transfusions, and adverse events within 3 months of surgery. RESULTS: The median length of stay was 10 days in the baseline group and only 5 days after the implementation of the standardised protocol and enhanced recovery program in series 4 (p <0.001). The percentage of patients discharged directly home was higher in series 4 than in the baseline group (84% vs. 66%, p = 0.085). Patients admitted to the hospital on the day of surgery increased from 2% in series 0 to 98% in series 4 (p <0.001). The use of urinary catheters was significantly higher in the baseline group (100% of patients) than in series 3 and 4 (0%) (p <0.001), and the number of patients who did not require opioids was significantly higher in series 4 than in series 0 (36% vs. 10%, p = 0.007). The median blood loss (500 ml vs. 300 ml, p <0.001), median difference in pre- and postoperative haemoglobin (29 g/dl vs. 25 g/dl, p = 0.145), and number of blood transfusions (5 vs. 2 p = 0.99) were higher in the baseline group than in series 4. The number of adverse events did not differ significantly between groups (p = 0.699). CONCLUSIONS: Almost all parameters examined in this study showed improvement, whereas the rate of adverse events was not affected and remained low. The presented data can be used as a benchmark, but details of these findings need to be confirmed in larger cohorts.
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瑞士一家医院在择期全髋关节置换术中逐步实施强化康复路径:一项队列研究
背景:已有研究表明,全髋关节置换术后的强化恢复计划可缩短住院时间,同时不影响手术效果,但目前还缺乏瑞士人群的相关数据。因此,这项回顾性队列研究评估了在瑞士医疗保健系统中是否存在类似的对临床结果的积极影响。方法:对接受择期初级全髋关节置换术的患者进行分析。基线组由一名外科医生在2013年根据临床实践指南连续治疗的50名患者组成。另一名外科医生于2014年4月实施了新的标准化治疗方案。2018年1月,在该方案之后又实施了一项强化恢复计划,整合了医院的所有医疗服务提供者。我们对基线组(0 系列)和四个系列各 50 名患者的数据进行了分析,其中两个系列采用标准化治疗方案(1-2 系列),两个系列采用增强型恢复计划(3-4 系列)。所有患者均在术后 6 周和 3 个月进行了随访。主要结果是住院时间和出院去向;次要结果是手术当天入院(而不是前一天入院)、导尿管的使用、阿片类药物的使用、术前和术后血红蛋白的差异、输血以及术后3个月内的不良事件。结果:基线组的中位住院时间为10天,而在系列4中,实施标准化方案和强化恢复计划后,中位住院时间仅为5天(P <0.001)。系列 4 中直接出院回家的患者比例高于基线组(84% 对 66%,p = 0.085)。手术当天入院的患者从系列 0 的 2% 增加到系列 4 的 98%(p <0.001)。基线组中导尿管的使用率(100%)明显高于系列 3 和系列 4(0%)(p <0.001),不需要阿片类药物的患者人数在系列 4 中明显高于系列 0(36% 对 10%,p = 0.007)。基线组的中位失血量(500 毫升对 300 毫升,p <0.001)、术前术后血红蛋白中位差(29 克/分升对 25 克/分升,p = 0.145)和输血次数(5 次对 2 次,p = 0.99)均高于系列 4。各组之间的不良事件数量无明显差异(P = 0.699):结论:本研究中几乎所有检查指标都有所改善,而不良反应发生率未受影响,仍然较低。所提供的数据可作为一个基准,但这些发现的细节还需要在更大的群体中得到证实。
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